Results 61 to 70 of about 11,060,985 (396)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Industry-driven innovative system development for the construction industry: The DIVERCITY project [PDF]
, 2004 Collaborative working has become possible using the innovative integrated systems in construction as many activities are performed globally with stakeholders situated in various locations.
Aouad, GF, Arayici, Y
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Designer/industry interface [PDF]
, 2008 The transcript from the discussion panel section of this event provides an interesting exchange of ideas around the notion of textile reuse and value. Following on from the exhibition Ever & Again: Experimental Recycled Textiles in October 2007, the ...
Earley, Rebecca
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
THE MECHANISM OF IMPLEMENTATION OF THE POLICYOF IMPORT SUBSTITUTION IN THE ARKHANGELSK REGION
Модернизация, инновация, развитие, 2016 In modern conditions of development of the world economy and the processes of globalization increasingly raises the question of the independence of the region from products that are necessary for the viability of the population purchased from third-party
N. Didenko, A. Kuzaeva
doaj +1 more source
Artificial Intelligence and the Internet of Things in Industry 4.0 [PDF]
, 2021 Petar Radanliev +4 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Submission to the Attorney-General’s Department on the Exposure Draft Telecommunications and Other Legislation Amendment Bill 2015 [PDF]
EXECUTIVE SUMMARY As has been stated in previous submissions to Government, the Associations acknowledge Government’s desire to protect telecommunications infrastructure and the information transmitted across it from unauthorised access and ...
Australian Industry Group +3 more
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