Results 91 to 100 of about 150,351 (307)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Философия и космология, 2016 The article investigates and further develops the Newton’s hypothesis about the origin of inertial forces. For this purpose the classic interpretation of light aberration phenomenon and the Lorentz — FitzGerald hypothesis — proposed to explain the ...
Alexandr Izbreht
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
On Causality, the Modern Contract and Inertia in “Climate Migration”
TecnoscienzaCommentary to the Lecture “Moving the immovable: Climate change and the multiple tensions between mobility and immobility”, by Huub Dijstelbloem (this issue).
Annalisa Pelizza
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Frontiers in Mechanical EngineeringIntroduction: With the rapid development of human society and economy, the power generation technology of various new energy vehicles has begun to receive widespread attention.Methods: Due to the lack of inertia and frequency stability in the new energy ...
Meng Du, Hailong Mei
doaj +1 more source
A novel control strategy of virtual synchronous generator in island micro-grids
Systems Science & Control Engineering, 2018 The control strategy of virtual synchronous generator (VSG) is an effective and efficient technique to provide frequency supporting for distributed generations.
Yong-jin Yu, Li-ke Cao, Xingmin Zhao
doaj +1 more source
Optimal CO2-abatement with socio-economic inertia and induced technological change [PDF]
The impact of induced technological change (ITC) in energy/climate models on the timing of optimal CO2-abatement depends on whether R&D or learning-by-doing (LBD) is the driving force. Bottom-up energy system models employing LBD suggest strong increases
Richard S.J. Tol, Malte Schwoon
core
Consumer Inertia and Dynamic Price Competition
The aim of this research is to study firms’ decisions about price and quality in a setting where consumers cannot fully evaluate products and must rely on anecdotal evidence to make choices.
Wiśnicki, Bartłomiej +1 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source