Results 71 to 80 of about 195,236 (290)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Demo 02-13 Inertia Cylinder

open access: yes, 2001
A heavy cylinder hangs by a thin rope from a rigid frame. A second identical thin rope is attached to the bottom of the cylinder, and a short metal rod is attached to the bottom end of the lower rope, as shown in Figure 1.

core  

Power System Inertia Estimation Using Synchrophasor Frequency Measurements [PDF]

open access: yes, 2021
A method includes performing by a processor: receiving a first plurality of power system frequency measurements from a plurality of phasor measurement units (PMUs) in the power system over a first time interval, generating a first plurality of multi ...
Liu, Yilu, Liu, Yong, Cui, Yi
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Consumption Inertia and Asymmetric Price Transmission [PDF]

open access: yes
We propose consumption inertia as a new explanation for asymmetric price transmission. Inertia in consumer demand enlarges retailers’ gains in gross profits from raising prices in response to higher wholesale prices and reduces gains from decreasing ...
Li, Xianghong, Xia, Tian
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

A matrix approach to determine optimal predictors in a constrained linear mixed model

open access: yesOpen Mathematics
For a general vector of all unknown vectors in a constrained linear mixed model (CLMM), this study compared the dispersion matrices of the best linear unbiased predictors with any symmetric matrix for determining the optimality of predictors among others.
Güler Nesrin, Büyükkaya Melek Eriş
doaj   +1 more source

Household’s Preferences and Monetary Policy Inertia [PDF]

open access: yes
The estimation of monetary policy rules suggests that the interest rates set by central banks move with a certain inertia. Although a number of hypotheses have been suggested to explain this phenomenon, its ultimate origin is unclear, thus delineating ...
Andrea Fracasso, Alessandro Flamini
core  

Inattention and Inertia in Household Finance: Evidence from the Danish Mortgage Market [PDF]

open access: yes, 2015
This paper studies the refinancing behavior of Danish households during a recent period of declining interest rates. Danish data are particularly suitable for this purpose because the Danish mortgage system imposes few barriers to refinancing, and ...
Andersen, Steffen   +3 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

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