Results 61 to 70 of about 195,236 (290)
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Interactions and consequences of inertia and switching costs
, 2012 Purpose:\ud Service research typically relates switching costs to customer loyalty, and portrays them as effective switching deterrents that engender harmful word-of-mouth (WOM).
Neale, Larry +3 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Australian PrescriberTherapeutic inertia, sometimes referred to as clinical inertia, has been defined as failure to initiate or intensify therapy when therapeutic goals are not reached. Lack of initiation or intensification of treatment according to clinical guidelines has been linked to suboptimal control of a range of chronic conditions. Clinician factors contributing to
openaire +2 more sources
Doing things collaboratively : realising the advantage or succumbing to inertia? [PDF]
, 2009 There has been much rhetoric about the value of strategic alliances, industry networks, public service delivery partnerships and many other collaborative forms, but reports of unmitigated success are not common.
Vangen, Siv, Huxham, Chris
core +2 more sources
IEEE AccessThis paper investigates the use of a battery energy storage system (BESS) to enhance the frequency response characteristics of a low-inertia power system following a disturbance or active power mismatch.
AKM Kamrul Hasan +2 more
doaj +1 more source
INERTIAL BEHAVIOUR AND THE SUSTAINABLE DEVELOPMENT OF THE FIRM [PDF]
Financial Studies, 2013 As increasingly obvious signs tell us that the natural environment is changing abruptly and, unfortunately, noticeably, the natural resources, while being increasingly depleted, have to support a growing population.
PhD Mihail DIMITRIU
doaj
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
, 2001 This demonstration shows the old magician's trick of pulling a silk tablecloth out from under a dining room setting without upsetting any of the items on the tablecloth.
core