Results 71 to 80 of about 28,590 (257)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A New Co-Evolution Binary Particle Swarm Optimization with Multiple Inertia Weight Strategy for Feature Selection

open access: yesInformatics, 2019
Feature selection is a task of choosing the best combination of potential features that best describes the target concept during a classification process.
Jingwei Too   +2 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Research on Short-Term Load Forecasting of LSTM Regional Power Grid Based on Multi-Source Parameter Coupling

open access: yesEnergies
Regional power grid load has strong periodicity and randomness, and its load characteristics are affected by many factors. Traditional short-term power load-forecasting methods have certain limitations in accuracy and stability, especially when dealing ...
Bo Li   +4 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Horizontal Bending Angle Optimization Method for Scraper Conveyor Based on Improved Bat Algorithm

open access: yesAlgorithms, 2019
The horizontal bending angle of scraper conveyor has a great influence on the running resistance, the current consumption, coal winning efficiency of the working surface, etc. Approximately 1–3° is usually the range of horizontal bending angle,
Ting Liu   +5 more
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

A Novel Method for Moments of Inertia Tuning for Free-flying Dynamically Similar Models via Simulated Annealing

open access: yesInternational Journal of Technology, 2017
In this study, a method was developed for tuning moments of inertia for a free-flying dynamically similar/scaled model of an aircraft. For this method, the simulated annealing optimization algorithm was used to obtain similar mass-inertial properties of ...
Ali Shakoori   +3 more
doaj   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki   +8 more
wiley   +1 more source

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