Results 51 to 60 of about 251,193 (292)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

LSEWOA: An Enhanced Whale Optimization Algorithm with Multi-Strategy for Numerical and Engineering Design Optimization Problems

open access: yesSensors
The Whale Optimization Algorithm (WOA) is a bio-inspired metaheuristic algorithm known for its simple structure and ease of implementation. However, WOA suffers from issues such as premature convergence, low population diversity in the later stages of ...
Junhao Wei   +6 more
doaj   +1 more source

Two-stage coaxial gas compressor [PDF]

open access: yes, 1972
Compressor raises pressure of gases from low ambient supply during space experiments by a system of low weight, size, and power input. Dc rotary-torque motor and ball-screw drive shaft activate first and second stage of compressor, utilizing inertia ...
Huniu, S.   +2 more
core   +1 more source

Computational spectroscopy of helium-solvated molecules: effective inertia, from small He clusters toward the nano-droplet regime

open access: yes, 2005
Accurate computer simulations of the rotational dynamics of linear molecules solvated in He clusters indicate that the large-size (nano-droplet) regime is attained quickly for light rotors (HCN, CO) and slowly for heavy ones (OCS, N$_2$O, CO$_2$), thus ...
Baroni, S.   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Path Planning Optimization of Smart Vehicle With Fast Converging Distance-Dependent PSO Algorithm

open access: yesIEEE Open Journal of Intelligent Transportation Systems
Path planning is a crucial technology and challenge in various fields, including robotics, autonomous systems, and intelligent transportation systems.
Muhammad Haris, Haewoon Nam
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A New Data Processing Approach for the SHPB Test Based on PSO-TWER

open access: yesApplied Sciences
This study addresses the challenge of accurately determining the arrival time of stress wave signals in SHPB test data processing. To eliminate human error, we introduce the time-window energy ratio method and evaluate six filters for noise reduction ...
Xuesong Wang, Zhenyang Xu, Lianjun Guo
doaj   +1 more source

Hyperbolic Tangent - Based Adaptive Inertia Weight Particle Swarm Optimization

open access: yesJurnal Nasional Teknik Elektro, 2023
This paper presents a study on using adaptive inertia weight (AIW) in particle swarm optimization (PSO) for solving optimization problems. An AIW function based on the hyperbolic tangent function was proposed, with the function parameters adaptively ...
Yaw Opoku Mensah Sekyere   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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