Results 71 to 80 of about 251,193 (292)
Connection Science, 2020 Feature selection is an important task to improve the classifier’s accuracy and to decrease the problem size. A number of methodologies have been presented for feature selection problems using metaheuristic algorithms.
Arfan Ali Nagra +6 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Journal of Engineering, 2019 The contaminants accumulated on the surface of transmission line insulator mainly come from the suspended particles in the air. Therefore, it is necessary to consider meteorological factors and environmental factors in the prediction of insulator ...
Rumeng Wang +3 more
doaj +1 more source
Water Science and Engineering, 2020 Based on conventional particle swarm optimization (PSO), this paper presents an efficient and reliable heuristic approach using PSO with an adaptive random inertia weight (ARIW) strategy, referred to as the ARIW-PSO algorithm, to build a multi-objective ...
Hai-tao Chen +3 more
doaj +1 more source
Adaptive particle swarm optimization [PDF]
, 2009 An adaptive particle swarm optimization (APSO) that features better search efficiency than classical particle swarm optimization (PSO) is presented. More importantly, it can perform a global search over the entire search space with faster convergence ...
Henry Shu-hung Chung +6 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
On the inertia of weighted (k - 1)-cyclic graphs
Ars Mathematica Contemporanea, 2015 Let G w be a weighted graph. The inertia of G w is the triple In( G w ) = ( i + ( G w ), i − ( G w ), i 0 ( G w )) , where i + ( G w ), i − ( G w ), i 0 ( G w ) are, respectively, the number of the positive, negative and zero eigenvalues of the adjacency matrix A ( G w ) of G w ...
Deng, Shibing, Li, Shuchao, Song, Feifei
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Energy Benefits of the Pantograph Wing Mechanism in Flapping Flight: Case Study of a Gull [PDF]
, 2015 Bird wings generally contain a 4-bar pantograph mechanism in the forearm that enables the wrist joint to be actuated from the elbow joint thus reducing the number of wing muscles and hence reducing the wing inertia and inertial drag.
Sattler, Gene D.
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source