Results 71 to 80 of about 334,891 (194)

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Potential of a digital parenting app to support parents of toddlers: Relations between the intensity of app use, language‐related parental self‐efficacy and the home literacy environment

British Educational Research Journal, EarlyView.
Abstract The home literacy environment (HLE) has a considerable influence on children's language development. How parents perceive their own parenting abilities (e.g., how well they encourage their children's language development) is particularly important when it comes to guiding their children appropriately through different stages of development ...
Luisa Prokupek, Theresia Hummel, Sabine Blaurock, Franziska Cohen, Yvonne Anders   +4 more
wiley   +1 more source

Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]

, 2003
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa, Harrod, Kathryn Shisler, Heywood, Patricia, VandeVusse, Leona   +3 more
core   +1 more source

Intentional Stent Fracture to Accommodate Growth After Coarctation Stenting in an 860‐g Neonate

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Congenital aortic coarctation in neonates and children can be managed with transcatheter stent implantation, but this approach raises the issue of how to accommodate the fixed stent structure within the growing vessel. Case Summary A 15‐month‐old boy, born prematurely with critical aortic coarctation, was treated at 1 week of age ...
Magdalena Cuman, Gernot Buheitel, Peter Ewert, Stanimir Georgiev   +3 more
wiley   +1 more source

Essential Components of Child Neurology Training: Program Director Consensus Recommendations

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We aimed to develop a program director–derived model of essential components of child neurology residency training. Methods All 79 child neurology residency programs in the United States were invited to submit a block diagram with 48 months of required rotations, the minimum clinical requirement across all approved pathways.
Danny Rogers, Robert Thompson Stone, Margie Ream, Rachel Pearson, Lindsay M. Pagano, Miya Elizabeth Bernson‐Leung, Elizabeth Troy, Scott I. Otallah, Eric Heath Kossoff, Sudha Kilaru Kessler, Clarimar Borrero‐Mejias, Daniel Crowder, Kathryn Idol Xixis, Salvatore C. Rametta, Stephen Deputy, Kapil Arya, Aaron Nelson, Jenny L. Wilson, Amy McGregor, Tara Mangum, Jennifer M. Bain, Yael Shiloh‐Malawsky, Meghan S. Candee, Donald L. Gilbert, Jan B. Wollack, Sharoon Qaiser, Rinat Jones, Jeffrey Strelzik, Emmanuelle Tiongson, Charu Venkatesan, Jessica Goldstein, Anna Thamann, Latanya D. Agurs, Teri L. Schreiner, Adam Wallace, Audrey Foster‐Barber, Rachel Gottlieb‐Smith   +36 more
wiley   +1 more source

Child Health Providers\u27 Precautionary Discussion of Emotions During Communication about Results of Newborn Genetic Screening [PDF]

, 2012
Objective To demonstrate a quantitative abstraction method for Communication Quality Assurance projects to assess physicians\u27 communication about hidden emotions after newborn genetic screening.
Christopher, Stephanie, Deuster, Lindsay, Farrell, Michael, Speiser, Jodi   +3 more
core   +1 more source

Pharmacomicrobiomics

Clinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich, Naama Geva‐Zatorsky, Rachel Herren, Libusha Kelly, Ziv Cohen, Haiying Zhou, Yi‐Ching Chen, Khalid Shah, Talin A. Robinson‐Catala, Grecia Frisby, Jason H. Karnes, Lisl Shoda   +11 more
wiley   +1 more source

Reproducibility and Diagnostic Utility of a Simplified Oil Red O Test in Infant Bronchoalveolar Lavage Samples

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Aspiration in infants is a diagnostic challenge. The lipid‐laden macrophage index (LLMI) developed in 1987 has been used as a supportive test; however, numerous recent studies have questioned its value and reproducibility. We evaluated a simplified LLMI in bronchoalveolar lavage (BAL) specimens from a pediatric cohort to assess ...
Emily Wheeler, Jennifer Kernodle‐Zimmer, Melissa Randolph, Harvey Cramer, Hector Mesa   +4 more
wiley   +1 more source