Results 51 to 60 of about 2,091 (217)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Lectura Conjunta como Promotora de la Adquisición del Lenguaje Infantil

Psicumex
El objetivo de la presente investigación fue analizar la influencia de la producción verbal de los cuidadores sobre la producción léxica de infantes (30 a 48 meses) mediante una actividad de lectura conjunta.
Ervin Ferreira Velasco, Paloma Suárez-Brito, Tania Valdés González, Elda Alicia Alva Canto   +3 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Detection of rotavirus and intestinal parasites in children under 5 years old, from indigenous communities in Zulia state, Venezuela

Kasmera, 2016
Rotavirus is a viral agent associated with childhood gastroenteritis, being with intestinal parasites, the principal cause of diarrhea in children. In order to detect rotavirus, and intestinal parasites in children from 0 to 5 years old of six indigenous
Aténcio Ricardo, Irama Perozo, Zulbey Rivero, Angela Bracho, Rafael Villalobos, Sergio Osorio, Maria Atencio   +6 more
doaj  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Algunos factores de riesgo de infecciones respiratorias agudas en menores de 5 años. Mayo 2014-2015

Multimed, 2017
RESUMEN Introducción: las enfermedades agudas del aparato respiratorio se presentan en su inmensa mayoría como infecciones, por lo cual en la actualidad se prefiere referirse a ellas como infecciones respiratorias agudas.
Lutgarda Cristina Martín Rodríguez, Gustavo Delgado Gutiérrez, Haydee Araujo Rodríguez, Idalmis Hernández Lastres, Rolando Figueredo Mendieta   +4 more
doaj  

Divulgación científica en Educación Primaria: aplicación e innovación más allá del aula

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias
La construcción de una ciudadanía que tome decisiones de forma crítica y basadas en el pensamiento científico es uno de los mayores retos de nuestros tiempos. La divulgación de la ciencia se posiciona como un valioso recurso para alcanzar este propósito,
Jesús Guillermo Flores Mejía, Belén Velázquez Gatica, María Guadalupe Bernal Vargas   +2 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source