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Current Treatment Options in Neurology, 2001
Infantile spasms is a catastrophic form of epilepsy found only in infants and young toddlers, with the peak incidence between 4 - 7 months of age. Estimated prevalence is 1 in 2000 - 6000 live births. There are many causes of infantile spasms, including tuberous sclerosis, hypoxic-ischaemic injury, congenital infectious diseases, inborn errors of ...
M, Wong, E, Trevathan
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Infantile spasms is a catastrophic form of epilepsy found only in infants and young toddlers, with the peak incidence between 4 - 7 months of age. Estimated prevalence is 1 in 2000 - 6000 live births. There are many causes of infantile spasms, including tuberous sclerosis, hypoxic-ischaemic injury, congenital infectious diseases, inborn errors of ...
M, Wong, E, Trevathan
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Epilepsia, 2021
We aimed to explore the feasibility of using scalp‐recorded high‐frequency oscillations (HFOs) to evaluate the efficacy and prognosis of adrenocorticotropic hormone (ACTH) treatment in patients with infantile spasms.
Wei Wang +14 more
semanticscholar +1 more source
We aimed to explore the feasibility of using scalp‐recorded high‐frequency oscillations (HFOs) to evaluate the efficacy and prognosis of adrenocorticotropic hormone (ACTH) treatment in patients with infantile spasms.
Wei Wang +14 more
semanticscholar +1 more source
Evolution of Infantile Spasms to Lennox-Gastaut Syndrome: What Is There to Know?
Journal of Child Neurology, 2021Objective: Children with infantile spasms may develop Lennox-Gastaut syndrome. The diagnostic criteria for Lennox-Gastaut syndrome are vague, and many experts use varying combinations of the following criteria for diagnosis: paroxysmal fast activity on ...
J. Nelson +4 more
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Journal of Child Neurology, 2021
Introduction: Perinatal arterial ischemic stroke (PAIS) underlies approximately 10% of infantile spasms (IS). We aim to identify patterns of brain injury in ischemic stroke that may predispose infants to infantile spasms.
R. Srivastava +4 more
semanticscholar +1 more source
Introduction: Perinatal arterial ischemic stroke (PAIS) underlies approximately 10% of infantile spasms (IS). We aim to identify patterns of brain injury in ischemic stroke that may predispose infants to infantile spasms.
R. Srivastava +4 more
semanticscholar +1 more source
Cost‐effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms
Epilepsia, 2021To compare the effectiveness and cost‐effectiveness of adrenocorticotropic hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we performed a systematic review, meta‐analysis, and cost‐effectiveness study.
Iván Sánchez Fernández +6 more
semanticscholar +1 more source
Neurologic Clinics, 1990
Infantile spasms are a seizure disorder in young infants with diverse etiologies, suggesting that they arise from any disturbance of central nervous system function during susceptible periods of development. The prognosis for normal intellectual and neurologic development parallels that of the underlying etiology.
G B, Bobele, J B, Bodensteiner
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Infantile spasms are a seizure disorder in young infants with diverse etiologies, suggesting that they arise from any disturbance of central nervous system function during susceptible periods of development. The prognosis for normal intellectual and neurologic development parallels that of the underlying etiology.
G B, Bobele, J B, Bodensteiner
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Vigabatrin for infantile spasms [PDF]
Pediatric Neurology, 2002 We reviewed 20 infants receiving vigabatrin for infantile spasms. Patients were not enrolled in a formal study. All families obtained the medication abroad. Age at initiation of vigabatrin ranged from 1 to 48 months; nine infants had received prior treatment with various antiepileptic medications. Patients were begun on the lowest practical dose of 125-
Wendy G. Mitchell, Namrata S. Shah
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Whole‐exome sequencing and adrenocorticotropic hormone therapy in individuals with infantile spasms
Developmental Medicine & Child Neurology, 2021To identify additional genes associated with infantile spasms using a cohort with defined infantile spasms.
S. Demarest +8 more
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Cochrane Database of Systematic Reviews, 2008
Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, the spasms, and an electroencephalogram (EEG) abnormality often called hypsarrhythmia. Psychomotor retardation is frequently found at follow up. Approximately two thirds of affected infants will have a detectable underlying neurological abnormality ...
John P. Osborne +2 more
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Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, the spasms, and an electroencephalogram (EEG) abnormality often called hypsarrhythmia. Psychomotor retardation is frequently found at follow up. Approximately two thirds of affected infants will have a detectable underlying neurological abnormality ...
John P. Osborne +2 more
openaire +4 more sources
Predictors of outcome among 31 children with infantile spasms syndrome.
Epileptic disorders, 2021OBJECTIVE Infantile spasms syndrome is a severe epileptic encephalopathy. Management of infantile spasms remains challenging because of pharmacoresistant forms and relapsing seizures.
A. Kvernadze +5 more
semanticscholar +1 more source