Results 141 to 150 of about 4,185,931 (303)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Appropriate Use Criteria for the Use of Nuclear Medicine in Musculoskeletal Infection Imaging. [PDF]

J Nucl Med, 2021
Palestro CJ, Clark A, Grady EE, Heiba S, Israel O, Klitzke A, Love C, Sathekge M, Ted T, Yarbrough TL.   +9 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Characterization of Left Ventricular Assist Device-Specific Infection by Whole-Body Parametric PET Imaging

Derlin T, Hanke JS, Werner RA, et al. Characterization of Left Ventricular Assist Device-Specific Infection by Whole-Body Parametric PET Imaging. Journal of Nuclear Medicine.
Czerner, Christoph, Ziegler, Sibylle I., Dogan, Günes, Ross, Tobias L., Schmitto, Jan D., Weiberg, Desiree, Werner, Rudolf A., Ruhparwar, Arjang, Bengel, Frank M., Hanke, Jasmin S., Schmack, Bastian, Derlin, Thorsten   +11 more
core   +1 more source

Integrating a covalent probe with ubiquicidin fragment enables effective bacterial infection imaging. [PDF]

RSC Med Chem, 2022
Bhatt Mitra J, Chatterjee S, Kumar A, Bandyopadhyay A, Mukherjee A.   +4 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

¹²³I-BMIPP, a Radiopharmaceutical for Myocardial Fatty Acid Metabolism Scintigraphy, Could Be Utilized in Bacterial Infection Imaging. [PDF]

Pharmaceutics, 2022
Muranaka Y, Mizutani A, Kobayashi M, Nakamoto K, Matsue M, Takagi F, Okazaki K, Nishi K, Yamazaki K, Nishii R, Shikano N, Okamoto S, Maki H, Kawai K.   +13 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Ultra-low dose infection imaging of a newborn without sedation using long axial field-of-view PET/CT. [PDF]

Eur J Nucl Med Mol Imaging, 2023
van Rijsewijk ND, van Leer B, Ivashchenko OV, Schölvinck EH, van den Heuvel F, van Snick JH, Slart RHJA, Noordzij W, Glaudemans AWJM.   +8 more
europepmc   +1 more source