Results 121 to 130 of about 4,185,931 (303)

Chronic Pulmonary Manifestations of COVID-19 Infection: Imaging Evaluation. [PDF]

Radiology, 2023
Murphy MC, Little BP.
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Combined Off-Resonance Imaging and T2 Relaxation in the Rotating Frame for Positive Contrast MR Imaging of Infection in a Murine Burn Model

, 2010
Purpose: To develop novel magnetic resonance (MR) imaging methods to monitor accumulation of macrophages in inflammation and infection. Positive-contrast MR imaging provides an alternative to negative-contrast MRI, exploiting the chemical shift ...
N. Psychogios, Laurence G. Rahme, O.C. Andronesi, D. Mintzopoulos, George Dai, Dionyssios Mintzopoulos, Jianxin He, RIGHI, VALERIA, G. Dai, AA Tzika, L.G. Rahme, Shingo Yasuhara, Meenu Kesarwani, J. He, Aria A. Tzika, M. Kesarwani, Nikolaos Psychogios, S. Yasuhara, Ovidiu C. Andronesi   +18 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Magnetization transfer analysis of brain tumor, infection, and infarction

, 2000
Magnetization transfer (MT) imaging has been used to characterize tissues. A prospective analysis of magnetization transfer ratio (MTR) was performed on 107 patients with brain tumors, infection, and infarction to determine its efficacy in differential ...
Pui, M H, M Tedeschi, A Covelli, E M Salvatore, M Quarantelli, A Larobina, E Ciarmiello, Alfano, M, B Brunetti   +9 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

In vivo imaging of mCMV infection in the eye

, 2009
In vivo imaging of mCMV infection in the ...
M Zinkernagel (13720525), Holly Chinnery (13053699), P McMenamin (13370031), M Degli-Esposti (13720534), C Petitjean (13720528), M Wikstrom (13369689)   +5 more
core  

Radionuclide imaging of musculoskeletal infection

, 2007
Radionuclide imaging studies are routinely used to evaluate patients suspected of having musculoskeletal infection. Three-phase bone imaging is readily available, relatively inexpensive, and very accurate in the setting of otherwise normal bone.
Charito Love, Christopher J. Palestro
core   +1 more source

Imaging and management of postoperative spine infection.

, 2014
Imaging evaluation of postoperative spinal infection is challenging. A systematic approach and keen understanding of multimodality imaging techniques, as well as knowledge of the patient\u27s surgical procedure and clinical presentation, are critical for
Gnerre, Jeffrey, Mazzie, Joseph P, Brooks, Michael K   +2 more
core   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science
Systemic lupus erythematosus (SLE) is a severe autoimmune disease characterized by hyperactive immune cells and excessive autoantigen accumulation. Dendritic cells (DC) can recognize multiple autoantigens and then leading to an inflammatory response ...
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
doaj   +1 more source