Results 41 to 50 of about 1,235,114 (296)

The HIV-associated tuberculosis epidemic--when will we act?

, 2010
Despite policies, strategies, and guidelines, the epidemic of HIV-associated tuberculosis continues to rage, particularly in southern Africa. We focus our attention on the regions with the greatest burden of disease, especially sub-Saharan Africa, and ...
Chimzizi, Rhehab, Corbett, Elizabeth L, De Cock, Kevin M, Harries, Anthony D, Harrington, Mark, Lawn, Stephen D, Maher, Dermot, Santos-Filho, Ezio T, Williams, Brian G, Zachariah, Rony   +9 more
core   +1 more source

The art of HIV elimination: past and present science [PDF]

, 2015
Introduction: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade ...
de Oliveira, T., Fisher, M., Lwuji, C.C., McGrath, N., Newell, M.-L., Newport, M., Pillay, D., Porter, K.   +7 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

The OneTogether collaborative approach to reduce the risk of surgical site infection: identifying the challenges to assuring best practice [PDF]

, 2015
Background: Surgical site infections (SSI) account for 16% of healthcare associated infections, and are associated with considerable morbidity, mortality and increased costs of care.
Gallagher, Rose, Neachell, Jonathan, Stott, Dawn, Topley, Katherine, Wilson, Jennie   +4 more
core   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Chlamydia psittaci infection in canaries heavily infested by Dermanyssus gallinae [PDF]

, 2011
Dermanyssus gallinae is a haematophagous ectoparasite responsible for anemia, weight loss, dermatitis and a decrease in egg production. Dermanyssus gallinae may play a role in the modulation of the host immune system, maybe predisposing the host to some ...
Cafiero, Maria Assunta, Camarda, Antonio, Circella, Elena, Pugliese, Nicola, Sparagano, Olivier, Todisco, Gianluca   +5 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Plasma procalcitonin levels remain low at the onset of gram-positive bacteremia regardless of severity or the presence of shock: A retrospective analysis of patients with detailed clinical characteristics

Journal of Microbiology, Immunology and Infection, 2021
Objectives: Procalcitonin (PCT) is an early diagnosis marker of sepsis/bacteremia. However, some reports refer to its lower responsiveness to gram-positive bacteremia.
Yusuke Koizumi, Daisuke Sakanashi, Tomoko Ohno, Akiko Nakamura, Atsuko Yamada, Yuichi Shibata, Arufumi Shiota, Hideo Kato, Mao Hagihara, Nobuhiro Asai, Masaya Watarai, Kenta Murotani, Yuka Yamagishi, Hiroyuki Suematsu, Hiroshige Mikamo   +14 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Semi-automated surveillance of surgical site infections using machine learning and rule-based classification models

npj Digital Medicine
Surgical site infections (SSIs), among the most frequent healthcare-associated infections, require surveillance, but traditional methods are labour-intensive.
Américo Agostinho, Etienne Chalot, Daniel Teixeira, Davide Bosetti, Niccolò Buetti, Gaud Catho, Stephan Harbarth, Mohamed Abbas   +7 more
doaj   +1 more source