Results 51 to 60 of about 696,071 (309)

Effectiveness of annual influenza campaigns and vaccination in reducing influenza burden in nursing homes of Canton Vaud in Switzerland

Antimicrobial Resistance and Infection Control
Background Influenza infections pose significant risks for nursing home (NH) residents. Our aim was to evaluate the impact of the cantonal influenza campaign, and influenza vaccination coverage of residents and healthcare workers (HCWs) on influenza ...
Emmanouil Glampedakis, Patricia Cuiña Iglesias, Flaminia Chiesa, Laetitia Qalla-Widmer, May-Kou Ku Moroni, Coralie Riccio, Béatrix Sobgoui, Marie Immaculée Nahimana Tessemo, Alessandro Cassini   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Artificial intelligence predicts healthcare workers’ antibiotic use intentions from psychological and behavioral measures across multiple theories

Scientific Reports
Antimicrobial resistance (AMR) remains a global health priority, partly driven by non-guideline-concordant antibiotic prescribing among healthcare workers.
Le Han, Peng Xian, Ying Liu, Xiao Liu, Yue Chang, Lijun Ma, Jie Ren, Yunshuang Liu, Xiaosong Wang, Yunjuan Long, Yuan Zhou, Li Ren, Fang Jin, Ling Liang, Hui Tang, Qi Liu   +15 more
doaj   +1 more source

Guidance on public reporting of healthcare-associated infections: recommendations of the Healthcare Infection Control Practices Advisory Committee [PDF]

"Embargoed until Monday, February 28, 2005 at 12:30 pm."Since 2002, 4 states have enacted legislation that requires health care organizations to publicly disclose health care-associated infection (HAI) rates.
Hospital Infection Control Practices Advisory Committee (U.S.)
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TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Infection Prevention and Control [PDF]

, 2020
AbstractHealthcare-associated infections (HAI) are adverse events exposing patients to a potentially avoidable risk of morbidity and mortality. Antimicrobial resistance (AMR) is increasingly contributing to the burden of HAIs and emerging as of the most alarming challenges for public health worldwide.
Giulio Toccafondi, Gaetano Pierpaolo Privitera, Giorgio Tulli, Anna Laura Costa   +3 more
openaire   +2 more sources

Infection prevention and control assessment tool for acute care hospitals [PDF]

Version 1.3.2 SEPT 2016This tool is intended to assist in the assessment of infection control programs and practices in acute care hospitals. If feasible, direct observations of infection control practices are encouraged.

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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Infection control in healthcare personnel : infrastructure and routine practices for occupational infection prevention and control services [PDF]

Updated: October 2019This document, Infection Control in Healthcare Personnel: Infrastructure and Routine Practices for Occupational Infection Prevention and Control Services, is an update of four sections of Part I of the Guideline for infection control

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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source