Results 61 to 70 of about 696,071 (309)

Competency level and determinants among infection prevention and control staff in the Middle East and North Africa region

open access: yesBMC Public Health
Background Competency of the staff working in infection prevention and control (IPC) is the cornerstone of successful IPC programs. The objective was to assess competency level and associated factors among IPC staff working in the Middle East and North ...
Majid M. Alshamrani   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Prognostic Value of MicroRNA Profiles in Septic Patients with Rare Hereditary Anemias: Insights from a Longitudinal Cohort Study

open access: yesInternational Journal of General Medicine
May AlMoshary,1,2 Nahid Abdulhamid Qushmaq,3 Abba Elgujja,4 Abdullah Mikki Alamoudi,4 Maha Abuhatlah AlQahtani,4 Hind Bugshan,4 Marytonia Valiyaveettil Antony,4 Fatimah Alshahrani3– 5 1Hematology and Transfusion Medicine, Department of Basic Science ...
AlMoshary M   +7 more
doaj  

Identification of pathogens causing fever in returning travelers using next-generation sequencing

open access: yesTropical Medicine and Health
Introduction In cases of fever following international travel, medical evaluation should consider the prevalence of infectious diseases in the travel destination. However, there are instances where a definitive diagnosis cannot be made. Identifying these
Kenji Gotoh   +4 more
doaj   +1 more source

Guidance for Infection Prevention and Control in K-12 Schools [PDF]

open access: yes
You can play an important role in helping your child have a healthy place to learn. The Centers for Disease Control and Prevention (CDC) developed guidance for schools to help students, families, and school staff keep kids healthy and learning.Guidance ...

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Emergence of coexisting blaNDM and mcr-1 genes in Escherichia coli isolates from the guts of healthy individuals

open access: yesMicrobiology Spectrum
The emergence of blaNDM/mcr-1-positive Escherichia coli poses a huge challenge to infection control. The purpose of this study was to investigate the plasmid and genomic characteristics of blaNDM/mcr-1-positive E.
Shuang Wang   +8 more
doaj   +1 more source

PREVENTION AND CONTROL OF HEALTHCARE ASSOCIATED INFECTIONS : Basic Recommendations [PDF]

open access: yes
This publication was made possible thanks to funding and cooperation from the Infection Control Center, U.S. Centers for Disease Control and Prevention, under Cooperative Agreement CDC-RFA-CK13-1301, \u201cBuilding Capacity and Networks to Address ...

core  

Implementing change in infection control practice : an action research study in two intensive care units. [PDF]

open access: yes, 1999
The increased emergence of bacterial resistance to antibiotics means that primary prevention of all hospital-acquired infections is essential, but ensuring that infection control practice is evidence-based requires reliable measurement of endemic ...
Sproat, L.J., Sproat, Louise Jane
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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