Results 61 to 70 of about 732,364 (302)

Infection control in healthcare personnel : infrastructure and routine practices for occupational infection prevention and control services [PDF]

Updated: October 2019This document, Infection Control in Healthcare Personnel: Infrastructure and Routine Practices for Occupational Infection Prevention and Control Services, is an update of four sections of Part I of the Guideline for infection control

core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Guidance for Infection Prevention and Control in K-12 Schools [PDF]

You can play an important role in helping your child have a healthy place to learn. The Centers for Disease Control and Prevention (CDC) developed guidance for schools to help students, families, and school staff keep kids healthy and learning.Guidance ...

core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Prognostic Value of MicroRNA Profiles in Septic Patients with Rare Hereditary Anemias: Insights from a Longitudinal Cohort Study

International Journal of General Medicine
May AlMoshary,1,2 Nahid Abdulhamid Qushmaq,3 Abba Elgujja,4 Abdullah Mikki Alamoudi,4 Maha Abuhatlah AlQahtani,4 Hind Bugshan,4 Marytonia Valiyaveettil Antony,4 Fatimah Alshahrani3– 5 1Hematology and Transfusion Medicine, Department of Basic Science ...
AlMoshary M, Qushmaq NA, Elgujja A, Alamoudi AM, AlQahtani MA, Bugshan H, Antony MV, Alshahrani F   +7 more
doaj  

Competency level and determinants among infection prevention and control staff in the Middle East and North Africa region

BMC Public Health
Background Competency of the staff working in infection prevention and control (IPC) is the cornerstone of successful IPC programs. The objective was to assess competency level and associated factors among IPC staff working in the Middle East and North ...
Majid M. Alshamrani, Elias Tannous, Fatmah Othman, Mohammed Al Zunitan, Mohammed Abalkhail, Aiman El-Saed   +5 more
doaj   +1 more source

Emergence of coexisting blaNDM and mcr-1 genes in Escherichia coli isolates from the guts of healthy individuals

Microbiology Spectrum
The emergence of blaNDM/mcr-1-positive Escherichia coli poses a huge challenge to infection control. The purpose of this study was to investigate the plasmid and genomic characteristics of blaNDM/mcr-1-positive E.
Shuang Wang, Lu Liu, Lei Du, Shanli Gao, Xiaolin Yu, Lixiao Cheng, Yuzhen Chen, Zengqiang Kou, Wenkui Sun   +8 more
doaj   +1 more source

PREVENTION AND CONTROL OF HEALTHCARE ASSOCIATED INFECTIONS : Basic Recommendations [PDF]

This publication was made possible thanks to funding and cooperation from the Infection Control Center, U.S. Centers for Disease Control and Prevention, under Cooperative Agreement CDC-RFA-CK13-1301, \u201cBuilding Capacity and Networks to Address ...

core  

Infection prevention and control programs evaluations: An exploratory comparative study of contemporary tolls

, 2019
Introduction: The efficacy of comprehensive Infection Prevention and Control Programs (IPCP) to reduce infection rates is well established. However, the evaluation of these programmes to achieve the best performance remains an issue.
Abraão, LM, Zimmerman, P-A, Padoveze, MC, Júnior, CN   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source