Results 81 to 90 of about 1,235,114 (296)

Bactericidal efficacy of meropenem in combination with cefmetazole against IMP-producing carbapenem-resistant Enterobacteriaceae

open access: yesBMC Research Notes, 2019
Objective Carbapenem-resistant Enterobacteriaceae (CRE) are among the most severe threats to public and clinical health because of their high levels of resistance to various antibiotics. We assessed the efficacy of combination therapy with meropenem (MEM)
Ryuichiro Abe   +5 more
doaj   +1 more source

The determinants of HIV infection and related sexual behaviors : evidence from Lesotho [PDF]

open access: yes
This paper analyzes the socioeconomic determinants of HIV infection and related sexual behaviors using the 2004Lesotho Demographic and Health Survey.
Corno, Lucia, de Walque, Damien
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Identification of pathogens causing fever in returning travelers using next-generation sequencing

open access: yesTropical Medicine and Health
Introduction In cases of fever following international travel, medical evaluation should consider the prevalence of infectious diseases in the travel destination. However, there are instances where a definitive diagnosis cannot be made. Identifying these
Kenji Gotoh   +4 more
doaj   +1 more source

Molecular aspects of MERS-CoV [PDF]

open access: yes, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Ahmed, Shamsah H.   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bodily waste management and related hygiene practices in nursing homes of Vaud: findings from a multicentre cross-sectional survey as a basis for targeted interventions

open access: yesAntimicrobial Resistance and Infection Control
Introduction Bodily waste management is a critical yet frequently neglected domain of infection prevention and control. We conducted a survey to examine various aspects of bodily waste management and related hygiene practices in nursing homes (NH) based ...
Emmanouil Glampedakis   +8 more
doaj   +1 more source

The economic control of infectious diseases [PDF]

open access: yes
Despite interesting work on infectious diseases by such economists as Peter Francis, Michael Kremer, and Tomas Philipson, the literature does not set out the general structure of externalities involved in the prevention, and care of such diseases.
Gersovitz, Mark, Hammer, Jeffrey S.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Risk Factors for Candidozyma auris Among Admitted Patients in Riyadh, Saudi Arabia (2020–2022)

open access: yesInfection and Drug Resistance
Fatimah S Alshahrani,1– 3 Abba Amsami Elgujja,3 Sarah Alsubaie,1,4 Salah Ezreqat,3 Ahmed Albarrag,1,5 Mazin Barry,1,2,6 Khalifa Binkhamis,5 Lulwah Alabdan,2,3 Hind Salih Bugshan,3 Dianah Rose Ledesma,3 Layla Abdulmonim Khalifa,3 Jesammal Santiago,3 ...
Alshahrani FS   +13 more
doaj  

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