Results 71 to 80 of about 654,521 (261)

Broadening the infection prevention and control network globally; 2017 Geneva IPC-think tank (part 3)

Antimicrobial Resistance and Infection Control, 2019
Background Healthcare-associated infection (HAI) is a major challenge for patient safety worldwide, and is further complicated by antimicrobial resistance (AMR) due to excessive antimicrobial use in both humans and animals.
Walter Zingg, Julie Storr, Benjamin J. Park, John A. Jernigan, Stephan Harbarth, M. Lindsay Grayson, Evelina Tacconelli, Benedetta Allegranzi, Denise Cardo, Didier Pittet, the 2017 Geneva-IPC Think Tank   +10 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Impact of Enhanced Infection Control Measures on Hospital-Acquired Carbapenem-Resistant Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii

Infection and Drug Resistance
Zihuan Li,1 Chuyu Lao,2 Huirong Wang,3 Tian Wang,1 Guanwen Lin,1 Huiwen Zhao,4 Maorui Lin,5 Ya Zou,1 Baohong Liu,1 Congrong Li,6 Yukun Lin,3 Cuiqiong Fan1 1Department of Infection Prevention and Control, The Affiliated Guangdong Second Provincial General
Li Z, Lao C, Wang H, Wang T, Lin G, Zhao H, Lin M, Zou Y, Liu B, Li C, Lin Y, Fan C   +11 more
doaj  

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Role of the nurses on antimicrobial stewardship team (AST) in single university hospital in Japan

Journal of Infection and Public Health, 2020
S. Miki, Y. Yuka, M. Yuki, K. Ai, K. Shunji, S. Arufumi, A. Nobuhiro, K. Yusuke, M. Hiroshige   +8 more
doaj   +1 more source

Infection Prevention and Control in the Workplace [PDF]

AAOHN Journal, 1986
R L, Messner, M N, Smith
openaire   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Influenza outbreak management tabletop exercise for congregate living settings

Antimicrobial Stewardship & Healthcare Epidemiology
We conducted a tabletop exercise on influenza outbreak preparedness that engaged a large group of congregate living settings (CLS), with improvements in self-reported knowledge and readiness.
Christina K. Chan, Jerome A. Leis, Heather Candon, Neethu R. Thomas, Jaclyn O’Brien, James Callahan, Brigitte Pascual, Marianna Ofner, Fatima Fazalullasha, Adrienne K. Chan, Jeff E. Powis, Charlie Tan   +11 more
doaj   +1 more source