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Immunosuppression in poultry production is a recurrent problem worldwide, and one of the major viral immunosuppressive agents is Infectious Bursal Disease Virus (IBDV). IBDV infections are mostly controlled by using live-attenuated vaccines.
Céline Courtillon+8 more
doaj +1 more source
Characteristics of Bursal T Lymphocytes Induced by Infectious Bursal Disease Virus [PDF]
ABSTRACTInfectious bursal disease virus (IBDV) is an avian lymphotropic virus that causes immunosuppression. When specific-pathogen-free chickens were exposed to a pathogenic strain of IBDV (IM), the virus rapidly destroyed B cells in the bursa of Fabricius. Extensive viral replication was accompanied by an infiltration of T cells in the bursa.
Hyungee Kim+4 more
openaire +3 more sources
Infectious Bursal Disease is a severe viral disease of chicken responsible for serious economic losses to poultry farmers. The causative agent, Infectious Bursal Disease virus, is inhibited by nitric oxide.
Bhaskar Ganguly+2 more
doaj +1 more source
The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]
In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Butter, Colin+4 more
core +1 more source
Host Combats IBDV Infection at Both Protein and RNA Levels
Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by infectious bursal disease virus (IBDV). In recent years, with the emergence of IBDV variants and recombinant strains, IBDV still threatens the ...
Shujun Zhang, Shijun Zheng
doaj +1 more source
Avian immunoglobulin-producing cell lines [PDF]
The present invention involves a method for preparing antibody-producing chicken cell clones. This method comprises a series of steps including initially immunizing a first chicken with a desired antigen.
Humphries, Eric H.
core +1 more source
Infectious bursal disease virus is an icosahedral polyploid dsRNA virus [PDF]
Viruses are a paradigm of the economy of genome resources, reflected in their multiplication strategy and for their own structure. Although there is enormous structural diversity, the viral genome is always enclosed within a proteinaceous coat, and most virus species are haploid; the only exception to this rule are the highly pleomorphic enveloped ...
Luque Buzo, Daniel+5 more
openaire +4 more sources
Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]
BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P+6 more
core +2 more sources
Recombinant vaccines and infectious bursal disease virus.
Abstract Infectious bursal disease virus (IBDV) is the aetiological agent of infectious bursal disease (IBD), an immunosuppressive and highly contagious disease that affects young birds causing important economic losses in the poultry industry worldwide.
Lucero, María Soledad+5 more
openaire +3 more sources
Genome Sequence of a Distinct Infectious Bursal Disease Virus [PDF]
ABSTRACT Infectious bursal disease virus is a relevant avian pathogen that affects poultry production. Here, we report the full-length coding sequence of the Uruguayan strain dIBDV/UY/2014/2202, isolated from a commercial broiler flock. The strain belongs to the distinct IBDV lineage that is widely distributed in South America.
Gonzalo Tomás+7 more
openaire +3 more sources