Results 211 to 220 of about 8,512 (263)
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Archives of Virology, 2007
Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 14 infectious bursal disease viruses (IBDVs) isolated in Tanzania from 2001 to 2004 were determined. Phylogenetic analysis showed that the isolates diverged into two genotypes and belonged to the very virulent (VV) type.
C. Kasanga +6 more
semanticscholar +3 more sources
Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 14 infectious bursal disease viruses (IBDVs) isolated in Tanzania from 2001 to 2004 were determined. Phylogenetic analysis showed that the isolates diverged into two genotypes and belonged to the very virulent (VV) type.
C. Kasanga +6 more
semanticscholar +3 more sources
Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary After oral infection with the highly virulent strain Cu-1 of IBDV, viral antigen can be detected at first four hr p. i. in macrophages and lymphoid cells of the caecum, one hr later also in such cells of the duodenum and jejunum. These cells are therefore to be considered as the place of first virus replication (organ of primary affinity ...
R. Müller +3 more
semanticscholar +3 more sources
Summary After oral infection with the highly virulent strain Cu-1 of IBDV, viral antigen can be detected at first four hr p. i. in macrophages and lymphoid cells of the caecum, one hr later also in such cells of the duodenum and jejunum. These cells are therefore to be considered as the place of first virus replication (organ of primary affinity ...
R. Müller +3 more
semanticscholar +3 more sources
Susceptibility of chicken blood lymphoblasts and monocytes to infectious bursal disease virus (IBDV)
Archives of Virology, 2005PHA-M stimulated lymphoblasts obtained from peripheral blood and separated from small lymphocytes by X 1 g velocity sedimentation, unstimulated blood lymphocytes, monocytes and cells isolated from the bursa of Fabricius of chickens, were infected in vitro by the pathogenic strain CU-1 of infectious bursal disease virus (IBDV). Six hours after infection
E. Burkhardt, H. Müller
semanticscholar +3 more sources
Avian Diseases, 2005
The evolution of very virulent (vv) infectious bursal disease virus (IBDV) has led to significant economic losses in many poultry-producing areas. Despite vigorous vaccination strategies, IBDV has been difficult to control. The protective efficacy of IBDV vaccines is traditionally evaluated in specific pathogen-free (SPF) chickens.
S. Rautenschlein +3 more
semanticscholar +3 more sources
The evolution of very virulent (vv) infectious bursal disease virus (IBDV) has led to significant economic losses in many poultry-producing areas. Despite vigorous vaccination strategies, IBDV has been difficult to control. The protective efficacy of IBDV vaccines is traditionally evaluated in specific pathogen-free (SPF) chickens.
S. Rautenschlein +3 more
semanticscholar +3 more sources
Veterinary Immunology and Immunopathology, 2020
T-cell immune responses were shown to play an important role in the regulation of infectious bursal disease virus (IBDV) replication and development of lesions in the bursa of Fabricius (BF) (bursal lesions) but also in the recovery from the infection.
Marina, Dobner +4 more
openaire +2 more sources
T-cell immune responses were shown to play an important role in the regulation of infectious bursal disease virus (IBDV) replication and development of lesions in the bursa of Fabricius (BF) (bursal lesions) but also in the recovery from the infection.
Marina, Dobner +4 more
openaire +2 more sources
Infectious bursal disease virus (IBDV) induces apoptosis in chicken B cells.
Comparative Immunology, Microbiology and Infectious Diseases, 2005The ability of infectious bursal disease virus (IBDV) serotypes 1 and 2, and the role of VP4 of both serotypes as well as the capacity of three IBDV intermediate serotype 1-specific vaccine strains to induce apoptosis in a chicken B-lymphocyte cell line, DT40, were investigated using the TUNEL technique.
J. Rodriguez-Lecompte +4 more
semanticscholar +3 more sources
Archives of Virology, 2015 In Argentina, classical vaccines are used to control infectious bursal disease virus (IBDV); however, outbreaks of IBDV are frequently observed. This could be due to failures in the vaccination programs or to the emergence of new strains, which would be able to break through the protection given by vaccines.
Federico Vera +6 more
semanticscholar +4 more sources
Veterinary Microbiology, 2019
The aim of the present study is to use Physalis mottle virus (PhMV) coat protein (CP) as a scaffold to display the neutralizing epitopes of Infectious bursal disease virus (IBDV) VP2. For this, three different chimeric constructs were synthesized by replacing the N-terminus of PhMV CP with tandem repeats of neutralizing epitopes of IBDV VP2 and ...
Kadagala Divya, Sahithi +5 more
openaire +2 more sources
The aim of the present study is to use Physalis mottle virus (PhMV) coat protein (CP) as a scaffold to display the neutralizing epitopes of Infectious bursal disease virus (IBDV) VP2. For this, three different chimeric constructs were synthesized by replacing the N-terminus of PhMV CP with tandem repeats of neutralizing epitopes of IBDV VP2 and ...
Kadagala Divya, Sahithi +5 more
openaire +2 more sources
Biotechnology Progress, 2006
The capsid of infectious bursal disease virus (IBDV), with a size of 60-65 nm, is formed by an initial processing of polyprotein (pVP2-VP4-VP3) by VP4, subsequent assemblage of pVP2 and VP3, and the maturation of VP2. In Sf9 cells, the processing of polyprotein expressed was restrained in the stage of VP2 maturation, leading to a limited production of ...
Meng-Shiou, Lee +4 more
openaire +2 more sources
The capsid of infectious bursal disease virus (IBDV), with a size of 60-65 nm, is formed by an initial processing of polyprotein (pVP2-VP4-VP3) by VP4, subsequent assemblage of pVP2 and VP3, and the maturation of VP2. In Sf9 cells, the processing of polyprotein expressed was restrained in the stage of VP2 maturation, leading to a limited production of ...
Meng-Shiou, Lee +4 more
openaire +2 more sources
Vaccine, 2012
Current infectious bursal disease virus (IBDV) vaccines suffer from maternal antibody interference and mimotope vaccines might be an alternative. Previously we demonstrated an IBDV VP2 five-mimotope polypeptide, 5EPIS, elicited protective immunity in chickens.
Yong-shan, Wang +7 more
openaire +2 more sources
Current infectious bursal disease virus (IBDV) vaccines suffer from maternal antibody interference and mimotope vaccines might be an alternative. Previously we demonstrated an IBDV VP2 five-mimotope polypeptide, 5EPIS, elicited protective immunity in chickens.
Yong-shan, Wang +7 more
openaire +2 more sources