Results 41 to 50 of about 2,044,342 (365)

A Dynamic Model for Infectious Diseases: The Role of Vaccination and Treatment [PDF]

Chaos, Solitons and Fractals, 2-Feb-2015, 2015
Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In this paper we propose a new model for infectious diseases spread having susceptible, infected, and recovered ...
arxiv   +1 more source

Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventions

Nature Communications, 2021
Estimating the effects of non-pharmaceutical interventions for COVID-19 is challenging, partly due to variations in testing. Here, the authors use viral sequence data as an alternative means of inferring intervention effects, and show that delays in ...
Manon Ragonnet-Cronin, Olivia Boyd, Lily Geidelberg, David Jorgensen, Fabricia F. Nascimento, Igor Siveroni, Robert A. Johnson, Marc Baguelin, Zulma M. Cucunubá, Elita Jauneikaite, Swapnil Mishra, Oliver J. Watson, Neil Ferguson, Anne Cori, Christl A. Donnelly, Erik Volz   +15 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Dynamics of multi-stage infections on networks [PDF]

, 2015
This paper investigates the dynamics of infectious diseases with a nonexponentially distributed infectious period. This is achieved by considering a multistage infection model on networks. Using pairwise approximation with a standard closure, a number of
AJ Black, AL Lloyd, AL Lloyd, CA Donnelly, CT Bauch, D Anderson, DR Cox, DT Gillespie, E Kenah, EH Kaplan, G Chowell, HJ Wearing, HTH Nguyen, HW Hethcote, I. Z. Kiss, J Ma, JC Miller, JM Hyman, JP Koplan, K Sharkey, K. B. Blyuss, KB Blyuss, KTD Eames, KTD Eames, L Danon, M Newman, M Newman, M Taylor, MEJ Newman, MI Meltzer, MJ Keeling, MJ Keeling, MJ Keeling, MJ Keeling, MJ Keeling, N MacDonald, N. Sherborne, NM Ferguson, NM Ferguson, NTJ Bailey, O Diekmann, O Diekmann, P Driessche van den, P Rattana, R Durrett, RE Hope-Simpson, RM Anderson, S Bansal, S Boccaletti, S Cauchemez, S Funk, S Riley, T House, T House, T House, TL Burr, V Andreasen, W Kermack, W-Y Chen, Z Feng   +59 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian, Glas, J., Herbinger, K. H., Hoelscher, Michael, Török, H.-P., Vilsmaier, F.   +5 more
core   +1 more source

Infectious Diseases

, 2016
As infectious diseases are very commonly seen in the ICU, this chapter covers both typical and atypical infections found in this setting. If the patient has been transferred to the ICU after a prolonged stay in the hospital, the treatment should be focused on a nosocomial infection.
Anand Shandilya, Surpreet Nagi
openaire   +2 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

You May Be Prepared, But Are You Ready? [PDF]

, 2019
Objective: Explain how planning and preparation is required to achieve readiness for infectious ...
Consuelos, Michael, MD, MBA
core   +1 more source

Clinical, Virological, Immunological, and Genomic Characterization of Asymptomatic and Symptomatic Cases With SARS-CoV-2 Infection in India

Frontiers in Cellular and Infection Microbiology, 2021
PurposeThe current global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to the investigation with clinical, biochemical, immunological, and genomic characterization from ...
Sanchari Chatterjee, Sanchari Chatterjee, Ankita Datey, Soumya Sengupta, Soumya Sengupta, Arup Ghosh, Atimukta Jha, Safal Walia, Sharad Singh, Sandhya Suranjika, Gargee Bhattacharya, Gargee Bhattacharya, Eshna Laha, Eshna Laha, Supriya Suman Keshry, Amrita Ray, Amrita Ray, Sweta Smita Pani, Amol Ratnakar Suryawanshi, Rupesh Dash, Shantibhusan Senapati, Tushar K. Beuria, Gulam Hussain Syed, Punit Prasad, Sunil Kumar Raghav, Satish Devadas, Rajeeb K. Swain, Soma Chattopadhyay, Ajay Parida   +28 more
doaj   +1 more source