Results 51 to 60 of about 2,398,984 (347)

The adverse effects of high‐dose corticosteroid on infectious and non‐infectious sequelae in renal transplant recipients with coronavirus disease‐19 in India [PDF]

, 2022
Vamsidhar Veeranki, Narayan Prasad, Jeyakumar Meyyappan, Dharmendra Bhadauria, Manas R. Behera, Ravi Kushwaha, Manas Ranjan Patel, Monika Yaccha, Anupama Kaul   +8 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Assessment of the influence of ABO blood groups on oral cholera vaccine immunogenicity in a cholera endemic area in Zambia

BMC Public Health, 2023
Background Histo-blood group antigens (HBGAs) which include the ABO and Lewis antigen systems have been known for determining predisposition to infections. For instance, blood group O individuals have a higher risk of severe illness due to V.
Caroline C. Chisenga, Samuel Bosomprah, Obvious N. Chilyabanyama, Peter Alabi, Michelo Simuyandi, John Mwaba, Harriet Ng’ombe, Natasha M. Laban, Charlie C. Luchen, Roma Chilengi   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK [PDF]

, 2021
Yuxuan Zhang, Chen Gong, Dawei Li, Zhiwei Wang, Shengda D. Pu, Alex W. Robertson, Hong Yu, John Parrington   +7 more
openalex   +1 more source

Emerging Infectious Diseases

Advances in Pediatrics, 2017
2017-08-25T16:30 ...
Department of Pediatrics, University of Colorado Health Sciences Center, The Children’s Hospital, Aurora, CO, USA ( host institution ), Rathore, Mobeen H. ( UF author ), Runyon, Jonathan ( author ), Haque, Tanveer-ul ( author )   +3 more
openaire   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Sexual and reproductive health services during outbreaks, epidemics, and pandemics in sub-Saharan Africa: a literature scoping review

Systematic Reviews, 2022
Background The COVID-19 pandemic could worsen adolescent sexual and reproductive health (ASRH). We sought evidence on the indirect impacts of previous infectious disease epidemics and the current COVID-19 pandemic on the uptake of ASRH in sub-Saharan ...
Mwila Ng’andu, Aldina Mesic, Jake Pry, Chanda Mwamba, Florence Roff, Jenala Chipungu, Yael Azgad, Anjali Sharma   +7 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source