Results 91 to 100 of about 285,146 (304)

Ratiometric Mycotoxin Detection in Living Plants With Dual‐Emissive Nanosensors

Advanced Materials, EarlyView.
A minimally invasive microneedle patch integrates carbon dot‐embedded metal–organic frameworks as nanosensors to detect a key fungal toxin in living plants. The nanosensor produces a ratiometric fluorescence signal that enables early, non‐destructive diagnosis of fungal infection before visible symptoms, offering a new biomaterials‐based strategy for ...
Yuliang Li, Di Shen, Ziyang Huang, Suppanat Puangpathumanond, Calvin Thenarianto, Yue Zhao, Jolly Madathiparambil Saju, Rajani Sarojam, Dongmei Zhou, Tedrick Thomas Salim Lew   +9 more
wiley   +1 more source

Potential risk of regional disease spread in west Africa through cross-border cattle trade [PDF]

, 2013
Transboundary animal movements facilitate the spread of pathogens across large distances. Cross-border cattle trade is of economic and cultural importance in West Africa.
Bassirou Bonfoh, Dean, A S, Fournié, G, Basel, G. Aboudou Boukaya (444126), Schelling Esther, Kulo Abalo E., Boukaya G. Aboudou, Kulo, Abalo E., Anna S. Dean (113917), Abalo E. Kulo (444125), Bonfoh Bassirou, Bonfoh, B, Lome, Swiss Tropical Inst, Bassirou Bonfoh (424496), Esther Schelling, Boukaya, G A, G Aboudou Boukaya, Bonfoh, Bassirou, Abalo E Kulo, Guillaume Fournié, Esther Schelling (113925), Boukaya, G. Aboudou, Fournié, Guillaume, Schelling, E, Fournié Guillaume, Schelling, Esther, Kulo, A E, Dean Anna S., Anna S Dean, Guillaume Fournié (160205), Dean, Anna S.   +32 more
core   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Laboratory methods for case finding in human psittacosis outbreaks: a systematic review

BMC Infectious Diseases, 2018
Background Psittacosis outbreak investigations require rapid identification of cases in order to trace possible sources and perform public health risk assessments.
Annelies A. Nieuwenhuizen, Frederika Dijkstra, Daan W. Notermans, Wim van der Hoek   +3 more
doaj   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Infectious disease surveillance for the London 2012 Olympic and Paralympic Games [PDF]

, 2012
The London 2012 Olympic and Paralympic Games will be one of the largest mass gathering events in British history. In order to minimise potential infectious disease threats related to the event, the Health Protection Agency (HPA) has set up a suite of ...
E Severi, M Catchpole, C Watson, Collective HPA Olympics Surveillance Work Group, E Heinsbroek   +4 more
core   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Mobile Phone–based Infectious Disease Surveillance System, Sri Lanka [PDF]

, 2010
Because many infectious diseases are emerging in animals in low-income and middle-income countries, surveillance of animal health in these areas may be needed for forecasting disease risks to humans.
Colin Robertson, Daniel, Samson L A, Stephen, Craig, Kate Sawford, Trisalyn A. Nelson, Craig Stephen, Sawford, Kate, Nelson, Trisalyn A, Samson L.A. Daniel, Robertson, Colin   +9 more
core   +1 more source

Physician reported incidence of early and late Lyme borreliosis

Parasites & Vectors, 2015
Background Lyme borreliosis is the most common vector-borne disease in Europe and North America. The objective of this study is to estimate the incidence of tick bites and Lyme borreliosis, representative of our entire country, including erythema migrans,
Agnetha Hofhuis, Margriet Harms, Sita Bennema, Cees C van den Wijngaard, Wilfrid van Pelt   +4 more
doaj   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source