Results 71 to 80 of about 285,146 (304)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Whole genome sequencing and phylogenetic analysis of dengue virus in Central Nepal from 2022 to 2023

BMC Global and Public Health
Background In Nepal, dengue is an emerging disease of growing concern as outbreaks are increasing in both size and geographic reach and beginning to affect areas previously thought dengue-free.
Margaret Chi, Nishan Katuwal, Aastha Shrestha, Surendra Kumar Madhup, Dipesh Tamrakar, Rajeev Shrestha   +5 more
doaj   +1 more source

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Vaccines, 2019
Influenza vaccination is recommended for nurses in China but is not mandatory or offered free of charge. The main objective of this study was to determine influenza vaccination coverage and the principal factors influencing influenza vaccination among ...
Jianxing Yu, Xiang Ren, Chuchu Ye, Keqing Tian, Luzhao Feng, Ying Song, Benjamin J. Cowling, Zhongjie Li   +7 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Meningococcal disease outbreak related to the World Scout Jamboree in Japan, 2015

Western Pacific Surveillance and Response, 2017
Problem: Six invasive meningococcal disease cases occurred among Scottish and Swedish nationals associated with the World Scout Jamboree (WSJ), an international mass gathering, held in Japan. The index case developed symptoms while returning home.
Mizue Kanai, Hajime Kamiya, Alison Smith-Palmer, Hideyuki Takahashi, Yushi Hachisu, Munehisa Fukusumi, Takehito Saitoh, Makoto Ohnishi, Tomimasa Sunagawa, Tamano Matsui, Kazunori Oishi   +10 more
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Surveillance of Infectious Diseases

, 2009
Surveillance is the ongoing, systematic collection, analysis, and interpretation of data essential to public health practice for public health action, closely integrated with the timely dissemination of these data to those who need to know. Modern surveillance systems must meet the challenges of a dynamic emergence of infectious diseases and the ...
Morgan, O.W., Pinner, R.W.
openaire   +1 more source

Imported infectious diseases and surveillance in Japan

Travel Medicine and Infectious Disease, 2008
Surveillance of imported infectious diseases is important because of the need for early detection of outbreaks of international concern as well as information of risk to the travelers. This paper attempts to review how the Japanese surveillance system deals with imported infectious diseases and reviews the trend of these diseases. The cases of acquired
Taniguchi, Kiyosu, Yoshida, Makiko, Sunagawa, Tomimasa, Tada, Yuki, Okabe, Nobuhiko   +4 more
openaire   +2 more sources

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven, N. Satyadev, A. E. M. Bastiaansen, Y. D. Piura, J. Kerstens, Y. S. Crijnen, J. Brenner, T. Brand, T. M. Bienfait, S. Veenbergen, J. M. de Vries, F. J. de Jong, E. G. P. Dopper, P. A. E. Sillevis Smitt, H. Seelaar, G. S. Day, M. J. Titulaer   +16 more
wiley   +1 more source

Syndromic surveillance of influenza-like illness in Scotland during the influenza A H1N1v pandemic and beyond [PDF]

, 2012
Syndromic surveillance refers to the rapid monitoring of syndromic data to highlight and follow outbreaks of infectious diseases, increasing situational awareness.
Murdoch, Heather, Crooks, George, Kavanagh, Kimberley, Jim McMenamin, Heather Murdoch, George Crooks, Robertson, Christopher, Chris Robertson, Kimberley Kavanagh, McMenamin, Jim   +9 more
core   +1 more source