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Global infectious disease surveillance
Infectious diseases remain the leading cause of death among children and young adults. They account for more than 13 million deaths a year with one in two deaths occurring in developing countries. Yet as the battle to control known infectious diseases continues new threats have emerged. Currently researchers are challenged by the resurgence of epidemic
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Infectious intestinal disease : do we know it all? [PDF]
Infectious intestinal disease (IID), with associated high morbidity and considerable mortality worldwide, causes a wide spectrum of illness. This ranges from mild discomfort to illness with severe complications.
Gauci, Charmaine +3 more
core
Vero cytotoxin-producing Escherichia coli in a study of infectious intestinal disease in England. [PDF]
An investigation of infectious intestinal disease in England included examination of feces for Vero cytotoxin-producing Escherichia coli (VTEC). Using DNA probe hybridization 27 VTEC strains were identified, 12 were from cases, and of these three ...
Willshaw, G.A. +20 more
core +1 more source
Surveillance of Infectious Diseases
Surveillance is the backbone of any disease control program. Data must be representative, timely, and consistent. Collection of data must be systematic. Analysis of data should include analysis by time, place, and person. Data sources can be varied, and have a potentially wide scope from death certification through clinical illness and from laboratory ...
openaire +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Background: Deaths in HIV-positive people have decreased since the introduction of highly active antiretroviral therapy (HAART) in 1996. Fewer AIDS-related deaths and an ageing cohort have resulted in an increase in the proportion of HIV patients dying ...
Sara Croxford, MSc +10 more
doaj +1 more source
Immunity induced by vaccination and infection, referred to as hybrid immunity, provides better protection against SARS-CoV-2 infections compared to immunity induced by vaccinations alone.
Gerco den Hartog +7 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Point source outbreaks of Campylobacter jejuni infection--are they more common than we think and what might cause them? [PDF]
Despite being the commonest bacterial cause of infectious intestinal disease (IID) in England and Wales, outbreaks of campylobacter infection are rarely reported.
Tam, CC +7 more
core +1 more source

