Results 91 to 100 of about 100,822 (272)

Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

open access: yesNature Communications
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats.
S. Riesle-Sbarbaro   +17 more
semanticscholar   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Dynamics of a Stochastic SEIR Epidemic Model with Vertical Transmission and Standard Incidence

open access: yesMathematics
A stochastic SEIR epidemic model with standard incidence and vertical transmission was developed in this work. The primary goal of this study was to determine whether stochastic environmental disturbances affect dynamic features of the epidemic model ...
Ruichao Li, Xiurong Guo
semanticscholar   +1 more source

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

open access: yesAdvanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen   +13 more
wiley   +1 more source

A mathematical model of vertically transmitted vector diseases

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2018
A mathematical model of vector-borne infectious diseases is presented, which takes into account the local interactions between reservoirs and vectors, as well as the transmission from vectors to dilution hosts.
Antonella Lupica, Annunziata Palumbo
doaj   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

open access: yesAdvanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam   +9 more
wiley   +1 more source

Control of mother-to-child transmission of infectious diseases in Brazil: progress in HIV/AIDS and failure in congenital syphilis Controle da transmissão vertical de doenças infecciosas no Brasil: avanços na infecção pelo HIV/AIDS e descompasso na sífilis congênita

open access: yesCadernos de Saúde Pública, 2007
In Brazil, syphilis and HIV infection are considered serious public health problems. However, in practice, epidemiological surveillance, prevention measures, and prenatal care seem to be more effective in the control of mother-to-child transmission of the HIV than in the control of transmission of the Treponema pallidum. Here we discuss the differences
Alberto Novaes Ramos Jr.   +4 more
openaire   +1 more source

Rapid response to an emerging infectious disease - Lessons learned from development of a synthetic DNA vaccine targeting Zika virus

open access: yesMicrobes and infection, 2018
Vaccines are considered one of the greatest advances in modern medicine. The global burden of numerous infectious diseases has been significantly reduced, and in some cases, effectively eradicated through the deployment of specific vaccines.
S. Kudchodkar   +13 more
semanticscholar   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Impact of COVID-19 in Pregnant Women and Vertical Transmission in Newborns; A Case Series

open access: yesPakistan Armed Forces Medical Journal
Objective: To assess the impact of COVID-19 in pregnant women and determine the vertical transmission in newborns. Study Design: Case series. Place and Duration of Study: Department of Gynecology & Obstetric, Combined Military Hospital, Gujranwala ...
Yasmin Fatima   +5 more
doaj   +1 more source

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