Results 81 to 90 of about 100,822 (272)

The SEIR Dynamical Transmission Model of Dengue Disease with and Without the Vertical Transmission of the Virus

, 2017
The transmission of dengue disease when there is a possibility of Vertical Transmission (VT) is studied using mathematical modeling. In the normal case, the mosquito is infected by the dengue virus when it bites an infectious human being.
Pratchaya Chanprasopchai, I. Tang, P. Pongsumpun   +2 more
semanticscholar   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Factors that affect mother-to-child HIV transmission at a university hospital in southern Brazil

Clinical and Biomedical Research, 2017
Objective: To evaluate factors that may interfere in mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV). Method: A historical cohort study with a sample of 299 HIV-infected mothers and their newborns who delivered at the Obstetric
Maria Aparecida Andreza Leopoldino, Eunice Beatriz Martin Chaves, Carmem Lúcia Oliveira da Silva, Helena von Eye Corleta   +3 more
doaj   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Prevalence and Factors Associated with Contraceptive Use among HIV-Infected Women of Reproductive Age Attending Infectious Disease Clinic at Gulu Regional Referral Hospital, Northern Uganda

BioMed Research International, 2018
Background Reproductive planning by HIV-infected women is essential, as it helps to prevent transmission of HIV to their unborn babies. Integrating contraceptive services to routine HIV care significantly increases the use of modern contraceptive methods,
F. Bongomin, Mercy Chelangat, Anthony Eriatu, Bruno Chan Onen, Priscilla Cheputyo, Stephen A Godmercy, Eddymond Ekuk, Francis Idony, James Henry Obol   +8 more
semanticscholar   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Stochastic and random models of Malaria Disease with vertical transmission

, 2017
Malaria is an infectious disease which affects both humans a nd animals. In this study, the existing mathematical model o f malaria disease with vertical transmission is analyzed in r andom enviroment.
T. Kesemen, M. Merdan, Z. Bekiryazici
semanticscholar   +1 more source

Vertical Transmission of COVID-19 to the Neonate

Infectious Diseases in Obstetrics and Gynecology, 2020
Objective To estimate the incidence rate of vertical transmission of coronavirus disease 2019 (COVID-19) to the neonate during the third trimester. Study Design.
S. Moreno, J. To, Hajoon Chun, Ivan M Ngai   +3 more
semanticscholar   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Projetos de vida de adultos jovens portadores de HIV por transmissão vertical: estudo exploratório com usuários de um ambulatório de infectologia Life projects of young adults with HIV acquired by vertical transmission: an exploratory study with patients of an infectious diseases' outpatients department

Saúde e Sociedade, 2012
Esta pesquisa teve o intuito de conhecer os projetos de vida de jovens adultos que convivem com o HIV/aids a partir da transmissão vertical, com relação a: estudo, trabalho e constituição familiar. Outro objetivo foi o de conhecer sua vivência no que diz respeito à assistência recebida. Como instrumentos, foram utilizados: questionário sociodemográfico
Lédice Lino de Oliveira, Marinella Della Negra, Maria Cezira Fantini Nogueira-Martins   +2 more
openaire   +1 more source