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Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
Nature, 2022 The SARS-CoV-2 Omicron BA.1 variant emerged in 20211 and has multiple mutations in its spike protein2. Here we show that the spike protein of Omicron has a higher affinity for ACE2 compared with Delta, and a marked change in its antigenicity increases ...
Adam Abdullahi +2 more
exaly +2 more sources
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
Nature Communications, 2020 SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally. We therefore compare the properties of the mutated S protein (SG614) with the original (SD614).
Lizhou Zhang, Cody B Jackson, Huihui Mou
exaly +2 more sources
Red Sea Bream Iridovirus Stability in Freeze–Thaw Cycles: Quantitative Assays of Infectious Particles [PDF]
AnimalsRed sea bream iridovirus is a serious threat to farmed fish, but little is known about how repeated freezing and thawing affect its stability.
Ji-Min Jeong +5 more
doaj +2 more sources
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
Nature, 2015 HIV-1 Nef and the unrelated mouse leukaemia virus glycosylated Gag (glycoGag) strongly enhance the infectivity of HIV-1 virions produced in certain cell types in a clathrin-dependent manner. Here we show that Nef and glycoGag prevent the incorporation of
Yoshiko Usami, Heinrich G Göttlinger
exaly +2 more sources
3-O Sulfated Heparan Sulfate (G2) Peptide Ligand Impairs the Infectivity of Chlamydia muridarum [PDF]
BiomoleculesBackground: Heparan sulfate (HS) is widely implicated as a receptor for Chlamydia cell attachment and infectivity. However, the enzymatic modification of HS modified by the 3-O sulfotransferase-3 (3-OST-3) enzyme in chlamydial cell entry remains unknown.
Weronika Hanusiak +9 more
doaj +2 more sources
Frontiers in Immunology, 2022 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has lasted more than 2 years with over 260 million infections and 5 million deaths worldwide as of November 2021.
Haolin Liu +9 more
doaj +1 more source
Antigenicity and infectivity characterization of SARS-CoV-2 BA.2.86
bioRxiv, 2023 The recently identified SARS-CoV-2 variant, BA.2.86, which carries a substantial number of Spike mutations, has raised a global alarm. An immediate assessment of its antigenic properties and infectivity is necessary.
Sijie Yang +20 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Contamination of fomites by human norovirus (HuNoV) can initiate and prolong outbreaks. Fomite swabbing is necessary to predict HuNoV exposure and target interventions. Historically, swab recovered HuNoV has been measured by molecular methods that detect
Katie N. Overbey +5 more
doaj +1 more source
Journal of Water and Health, 2022 The current COVID-19 pandemic has emphasized the vulnerability of communities living in the urban outskirts and informal settlements. The lack of reliable COVID-19 case data highlights the importance and application of wastewater-based epidemiology. This
Mikaela Renata Funada Barbosa +19 more
doaj +1 more source