Results 101 to 110 of about 188,793 (261)

Infectivity of tumor cell-adapted rotavirus isolates compared with the infectivity of their respective parental versions.

, 2016
Infectivity of tumor cell-adapted rotavirus isolates compared with the infectivity of their respective parental versions.
Orlando Acosta (2142832), Emiliano Barreto (2142841), Elver Silva (2142838), Rafael A. Guerrero (2142835), Carlos A. Guerrero (1264551)   +4 more
core   +1 more source

Bioassay studies support the potential for iatrogenic transmission of variant Creutzfeldt Jakob Disease through dental procedures [PDF]

, 2012
<p>Background: Evidence is required to quantify the potential risks of transmission of variant Creutzfeldt Jakob (vCJD) through dental procedures. Studies, using animal models relevant to vCJD, were performed to address two questions.
Elizabeth Kirby (115076), Marsh, PD, Raven, N.D.H., Mark Cornwall, Andrew Smith (11197), Marsh Philip D., Vassey, M., Neil McLeod (115085), Cornwall Mark, Joanne Dickinson (115078), J. Mark Sutton (115091), Cornwall, M, Dickinson, J., Dickinson Joanne, Vassey Matthew, Mark Cornwall (115083), Raven, NDH, Matthew Vassey (115080), Mike Dennis, Walker, J.T., Kirby Elizabeth, Smith, A, McLeod, N., J Mark Sutton, Walker, JT, Dennis, M., Sutton, J.M., Matthew Vassey, Philip D. Marsh (115087), James T Walker, Marsh, P.D., Dennis, M, Joanne Dickinson, McLeod Neil, McLeod, N, Andrew Smith, Walker James T., Elizabeth Kirby, Raven Neil D. H., Smith, A., Vassey, M, Neil D. H. Raven (115095), James T. Walker (115089), Dickinson, J, Sutton, JM, Sutton J. Mark, Kirby, E, Kirby, E., Smith Andrew, Neil McLeod, Cornwall, M., Mike Dennis (115082), Philip D Marsh, Neil D H Raven, Dennis Mike   +54 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Time course infectivity experiments.

, 2017
Time course infectivity experiments.
Jyutika M. Rajwade (3612044), Vimal Sugumar (3612050), Gani Taju (3612053), Prabir Kumar Kulabhusan (3612056), A. S. Sahul Hameed (3612047), Kishore M. Paknikar (2470024)   +5 more
core   +1 more source

Risk of HIV transmission by healthcare workers – a systematic review

GMS Hygiene and Infection Control
Background: Occupational HIV infection among healthcare workers (HCWs) has declined markedly in high-income countries as a result of improved infection prevention and control, safety-engineered devices, and the widespread availability of antiretroviral ...
Roland Diel, Rene Gottschalk, Albert Nienhaus   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus

mBio, 2017
Persistent, high-risk human papillomavirus (HPV) infection is the primary cause of cervical cancer. Neutralizing antibodies elicited by L1-only virus-like particles (VLPs) can block HPV infection; however, the lack of high-resolution structures has ...
Zhihai Li, Daning Wang, Ying Gu, Shuo Song, Maozhou He, Jingjie Shi, Xinlin Liu, Shuangping Wei, Jinjin Li, Hai Yu, Qingbing Zheng, Xiaodong Yan, Timothy S. Baker, Jun Zhang, Jason S. McLellan, Shaowei Li, Ningshao Xia   +16 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Small critical RNAs in the scrapie agent [PDF]

, 2009
Unconventional infectious agents cause transmissible spongiform encephalopathy (TSE) diseases including scrapie and bovine spongiform encephalopathy (BSE) in animals and Creutzfeldt-Jakob disease in humans. The protein only hypothesis claims that the TSE
Marie-Madeleine Ruchoux, Jean-Philippe Deslys, Nicolas Vignier, Pierre Lebon, Jean-Guy Fournier, Sophie Freire, Emmanuel Comoy, Steve Simoneau   +7 more
core