Results 71 to 80 of about 518,510 (312)

Local rabies transmission and regional spatial coupling in European foxes.

PLoS ONE, 2020
Infectious diseases are often transmitted through local interactions. Yet, both surveillance and control measures are implemented within administrative units.
Laurie Baker, Jason Matthiopoulos, Thomas Müller, Conrad Freuling, Katie Hampson   +4 more
doaj   +1 more source

Fitting complex ecological point process models with integrated nested Laplace approximation

, 2013
Summary 1. We highlight an emerging statistical method, integrated nested Laplace approximation (INLA), which is ideally suited for fitting complex models to many of the rich spatial data sets that ecologists wish to analyse. 2.
Gallego-Fernández, Juan B., Travis, Justin M. J., Illian, Janine Baerbel, Esquivias, M. Paz, Martino, Sara, Zunzunegui, Maria, Illian, Janine B., Warton, David, Sørbye, Sigrunn H., Travis, Justin M.   +9 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

inlabru: an R package for Bayesian spatial modelling from ecological survey data

Methods in Ecology and Evolution, 2019
Spatial processes are central to many ecological processes, but fitting models that incorporate spatial correlation to data from ecological surveys is computationally challenging. This is particularly true of point pattern data (in which the primary data
F. Bachl, F. Lindgren, D. Borchers, J. Illian   +3 more
semanticscholar   +1 more source

A Preliminary Study on Mapping Methods of Geographical Features of Archaeological Remains and Ancient Human Behaviors in Prehistoric Settlement Landscape Reconstruction

ISPRS International Journal of Geo-Information
The reconstruction of ancient geographical scenarios is significant for understanding environmental changes and civilizational evolution. However, human activities, as the main subjects in these scenes, cannot be directly reconstructed due to the lack of
Lin Yang, Hui Li, Peng Yu, Weihong Wu
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Hidden state inference requires abstract contextual representations in ventral hippocampus

bioRxiv
The ability to form and utilize subjective, latent contextual representations to influence decision making is a crucial determinant of everyday life. The hippocampus is widely hypothesized to bind together otherwise abstract combinations of stimuli to ...
Karyna Mishchanchuk, Gabrielle C Gregoriou, Albert J. Qü, Alizée Kastler, Q. Huys, Linda Wilbrecht, A. Macaskill   +6 more
semanticscholar   +1 more source

Spatial confounding in joint species distribution models

Methods in Ecology and Evolution
Joint species distribution models (JSDMs) are a popular method for analysing multivariate abundance data, with important applications such as uncovering how species communities are driven by environmental processes, model‐based ordination to visualise ...
Francis K. C. Hui, Quan Vu, Mevin B. Hooten   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Spatial sampling on streams: principles for inference on aquatic networks

, 2014
For ecological and environmental data, prior inquiries into spatial sampling designs have considered two‐dimensional domains and have shown that design optimality depends on the characteristics of the target spatial domain and intended inference.
Nicholas A. Som, P. Monestiez, Jay M. Ver Hoef, D. Zimmerman, E. Peterson   +4 more
semanticscholar   +1 more source