Results 11 to 20 of about 26,939 (224)

Deterministic, stochastic, and mean-field PDE models in neuroscience [PDF]

open access: yesFrontiers in Computational Neuroscience
Large neuronal networks demonstrate complex dynamics across multiple scales, ranging from single-neuron excitability and spike-train variability to mesoscopic rhythms and whole-brain activity.
Coşkun Çetin   +5 more
doaj   +2 more sources

Bayesian inference of mixed Gaussian phylogenetic models [PDF]

open access: yesBMC Bioinformatics
Background Continuous traits evolution of a group of taxa that are correlated through a phylogenetic tree is commonly modelled using parametric stochastic differential equations to represent deterministic change of traits through time, while ...
Bayu Brahmantio   +2 more
doaj   +2 more sources

Quantifying Parameter Interdependence in Stochastic Discrete Models of Biochemical Systems

open access: yesEntropy, 2023
Stochastic modeling of biochemical processes at the cellular level has been the subject of intense research in recent years. The Chemical Master Equation is a broadly utilized stochastic discrete model of such processes.
Samaneh Gholami, Silvana Ilie
doaj   +1 more source

“Exact” and Approximate Methods for Bayesian Inference: Stochastic Volatility Case Study

open access: yesEntropy, 2021
We conduct a case study in which we empirically illustrate the performance of different classes of Bayesian inference methods to estimate stochastic volatility models.
Yuliya Shapovalova
doaj   +1 more source

Quantifying biochemical reaction rates from static population variability within incompletely observed complex networks.

open access: yesPLoS Computational Biology, 2022
Quantifying biochemical reaction rates within complex cellular processes remains a key challenge of systems biology even as high-throughput single-cell data have become available to characterize snapshots of population variability.
Timon Wittenstein   +2 more
doaj   +1 more source

Scalable and flexible inference framework for stochastic dynamic single-cell models.

open access: yesPLoS Computational Biology, 2022
Understanding the inherited nature of how biological processes dynamically change over time and exhibit intra- and inter-individual variability, due to the different responses to environmental stimuli and when interacting with other processes, has been a
Sebastian Persson   +7 more
doaj   +1 more source

Retrieval of process rate parameters in the general dynamic equation for aerosols using Bayesian state estimation: BAYROSOL1.0 [PDF]

open access: yesGeoscientific Model Development, 2021
The uncertainty in the radiative forcing caused by aerosols and its effect on climate change calls for research to improve knowledge of the aerosol particle formation and growth processes.
M. Ozon   +5 more
doaj   +1 more source

Building an adaptive trait simulator package to infer parametric diffusion model along phylogenetic tree

open access: yesMethodsX, 2020
The development of an adaptive trait simulator package for inferring trait evolution along a phylogenetic tree is shown. Stochastic processes of the continuous type are broadly applied to modeling trait evolution when the evolutionary relationship among ...
Dwueng-Chwuan Jhwueng
doaj   +1 more source

Systematic comparison of modeling fidelity levels and parameter inference settings applied to negative feedback gene regulation.

open access: yesPLoS Computational Biology, 2022
Quantitative stochastic models of gene regulatory networks are important tools for studying cellular regulation. Such models can be formulated at many different levels of fidelity. A practical challenge is to determine what model fidelity to use in order
Adrien Coulier   +3 more
doaj   +1 more source

Inference for nonlinear epidemiological models using genealogies and time series. [PDF]

open access: yesPLoS Computational Biology, 2011
Phylodynamics - the field aiming to quantitatively integrate the ecological and evolutionary dynamics of rapidly evolving populations like those of RNA viruses - increasingly relies upon coalescent approaches to infer past population dynamics from ...
David A Rasmussen   +2 more
doaj   +1 more source

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