Results 121 to 130 of about 3,947,093 (294)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

An inference mechanism for question answering

Journal of Computer Science and Technology, 2007
Facultad de ...
Roger, Sandra, Ferrández, Sergio, López Moreno, Pilar, Peral, Jesús   +3 more
openaire   +3 more sources

Delayed predictive inference integration with and revision by low-competitive inference alternatives in Chinese narrative text reading

Frontiers in Psychology
When readers encounter information conflicting with the predictive inferences made earlier, they may update the outdated ones with new ones, a process known as predictive inference revision.
Fei Xu, Lulu Cheng, Xianghong Gong, Chenglong Liu   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Machine Learning Inference of Gene Regulatory Networks in Developing Mimulus Seeds

Plants
The angiosperm seed represents a critical evolutionary breakthrough that has been shown to propel the reproductive success and radiation of flowering plants.
Albert Tucci, Miguel A. Flores-Vergara, Robert G. Franks   +2 more
doaj   +1 more source

Asymptotic and bootstrap inference for inequality and poverty measures [PDF]

A random sample drawn from a population would appear to offer an ideal opportunity to use the bootstrap in order to perform accurate inference, since the observations of the sample are IID.
Russell Davidson, Emmanuel Flachaire
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Intersection bounds: estimation and inference [PDF]

We develop a practical and novel method for inference on intersection bounds, namely bounds defined by either the infimum or supremum of a parametric or nonparametric function, or equivalently, the value of a linear programming problem with a potentially ...
Adam Rosen, Victor Chernozhukov, Sokbae 'Simon' Lee   +2 more
core  

State-Space Inference and Learning with Gaussian Processes [PDF]

, 2010
18.10.13 KB. Ok to add author version to spiral, authors hold copyright.State-space inference and learning with Gaussian processes (GPs) is an unsolved problem.
Rasmussen, Carl E, Deisenroth, Marc P, Deisenroth, M., Turner, Ryan, Rasmussen, C., Turner, R.   +5 more
core