Results 41 to 50 of about 3,428 (174)

Dysregulation of GABAergic System in the Hippocampus and Inferior Colliculi of Rats during the Development of Audiogenic Epilepsy [PDF]

open access: green, 2023
Andrey P. Ivlev   +5 more
openalex   +1 more source

Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin‐Sensitive Magnetic Resonance Imaging and 18F‐Fluorodopa‐Positron Emission Tomography

open access: yesMovement Disorders, Volume 40, Issue 4, Page 716-726, April 2025.
Abstract Background Central synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), involve alpha‐synuclein accumulation and dopaminergic cell loss in the substantia nigra (SN) and locus coeruleus (LC).
Paula Trujillo   +10 more
wiley   +1 more source

Glaucoma animal models in rabbits: State of the art and perspectives—A review

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 3, Page 429-440, March 2025.
Glaucoma, a visual thief, is characterized by elevated intraocular pressure (IOP) and loss of retinal ganglion cells (RGCs). Selecting suitable animals for preclinical models is of great significance in research on the prevention, early screening, and effective treatments of glaucoma.
Rong Hu   +4 more
wiley   +1 more source

A Viral Labelling Study of Spinal Trigeminal Nucleus Caudalis Projection Neurons Targeting the Parabrachial Nucleus

open access: yesJournal of Neurochemistry, Volume 169, Issue 3, March 2025.
Using adeno‐associated viral vectors (AAVs) to label projection neurons (PN) that link nervous system regions is a powerful tool in neuroscience for studying circuitry and function. However, AAVs exhibit tropism, which can produce variable expression depending on the viral serotype and the CNS region targeted.
Sophie Maric   +4 more
wiley   +1 more source

Evaluating the In Vivo Specificity of [18F]UCB-H for the SV2A Protein, Compared with SV2B and SV2C in Rats Using microPET

open access: yesMolecules, 2019
The synaptic vesicle protein 2 (SV2) is involved in synaptic vesicle trafficking. The SV2A isoform is the most studied and its implication in epilepsy therapy led to the development of the first SV2A PET radiotracer [18F]UCB-H.
Maria Elisa Serrano   +11 more
doaj   +1 more source

Locus Coeruleus Degeneration in Essential Tremor With Mild Cognitive Impairment: A Neuromelanin MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 1, January 2025.
Using neuromelanin‐sensitive‐MRI (NM‐MRI) analysis, we found the integrity of locus coeruleus (LC) was decreased in ET patients and be more pronounced in ET‐MCI patients. The decreased integrity of LC was correlated with the severity of cognitive functions, suggesting some pathological changes of LC contribute to the cognitive impairment in ET ...
Yuelin Fang   +13 more
wiley   +1 more source

Dorsolateral pontine lesions produce distinct ocular motor abnormalities with anatomical correlations

open access: yesEuropean Journal of Neurology, Volume 32, Issue 1, January 2025.
Abstract Background and Purpose The dorsolateral portion of the caudal pons contains the vestibular nucleus (VN) and inferior cerebellar peduncle (ICP) that play important roles in conveying and processing vestibular and ocular motor signals. This study aimed to characterize ocular motor abnormalities along with their anatomical correlations in ...
Hyun Sung Kim   +4 more
wiley   +1 more source

Measurement of Anteroposterior diameters of normal brainstem by Magnetic Resonance Imaging

open access: yesJournal of Gandaki Medical College, 2019
Aim: The aim of this study is to assess the anteroposterior diameter of brainstem (midbrain, pons and medulla) of normal Nepalese people to establish normal ranges and to correlate the measurement with pa­tient’s age and gender. Method: The study is a
S. Singh   +3 more
doaj   +1 more source

Multi‐Night Electroencephalography Reveals Positive Association Between Sleep Efficiency and Hippocampal Subfield and Entorhinal Cortex Volumes in Healthy Aging

open access: yesHuman Brain Mapping, Volume 45, Issue 18, December 15, 2024.
In a sample of 118 fifty to 80‐year‐old healthy adults, multi‐night recordings of portable electroencephalography (EEG) revealed associations between hippocampal subfield and entorhinal cortex volumes and sleep that were otherwise not detected by subjective sleep measures.
Attila Keresztes   +11 more
wiley   +1 more source

One hundred ways to process time, frequency, rate and scale in the central auditory system: a pattern-recognition meta-analysis

open access: yesFrontiers in Computational Neuroscience, 2015
The mammalian auditory system extracts features from the acoustic environment based on the responses of spatially distributed sets of neurons in the subcortical and cortical auditory structures.
Edgar eHemery, Jean-Julien eAucouturier
doaj   +1 more source

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