Results 51 to 60 of about 3,498 (148)

Transcortical photothrombotic pyramidotomy model with persistent motor deficits.

open access: yesPLoS ONE, 2018
Traditional pyramidotomy models have a high mortality rate from breathing difficulties and show early recovery from the induced motor deficits. This study establishes a novel pyramidotomy technique in Sprague Dawley rats that generates persistent motor ...
Hanlim Song   +8 more
doaj   +1 more source

The Brain of the African Wild Dog. V. The Somatosensory System and Vestibular Nuclear Complex

open access: yesJournal of Comparative Neurology, Volume 533, Issue 7, July 2025.
Lateral view of the African wild dog brain showing the location of the somatosensory cortical areas in relation to the parietal multisensory region (PP), occipital visual cortical areas (17, 18, 19, 21, SS, T), and temporal auditory cortical areas (AAF, AI AII).
Samson Chengetanai   +6 more
wiley   +1 more source

Sex-Specific Brain Deficits in Auditory Processing in an Animal Model of Cocaine-Related Schizophrenic Disorders

open access: yesBrain Sciences, 2013
Cocaine is a psychostimulant in the pharmacological class of drugs called Local Anesthetics. Interestingly, cocaine is the only drug in this class that has a chemical formula comprised of a tropane ring and is, moreover, addictive.
Patricia A. Broderick, Taylor Rosenbaum
doaj   +1 more source

Hearing Function in Spinal and Bulbar Muscular Atrophy (SBMA): A Case Control Study From a Tertiary Referral Center

open access: yesEuropean Journal of Neurology, Volume 32, Issue 6, June 2025.
ABSTRACT Background Expanding on earlier findings of auditory involvement from two small‐scale studies, we conducted a comprehensive evaluation of hearing levels in a larger cohort of SBMA patients. Methods Thirty‐six SBMA patients and 36 age‐matched male controls without risk factors for hearing loss underwent a comprehensive audiological assessment ...
Lorenzo Blasi   +11 more
wiley   +1 more source

Time‐restricted feeding mitigates Alzheimer's disease‐associated cognitive impairments via a B. pseudolongum‐propionic acid‐FFAR3 axis

open access: yesiMeta, Volume 4, Issue 2, April 2025.
A 4‐month of time‐restricted feeding (TRF) intervention alleviated cognitive impairments in Alzheimer's disease (AD) patients, while a 3‐month TRF regimen improved spatial memory, reduced amyloid‐beta accumulation, and promoted microglial aggregation around plaques in AD mice. Antibiotic‐induced gut microbiota depletion partly abolished TRF's benefits.
Yihang Zhao   +15 more
wiley   +1 more source

Editorial: The Jilted Brain: Neglected Structures and Functions

open access: yesFrontiers in Systems Neuroscience, 2021
Regina A. Mangieri   +2 more
doaj   +1 more source

Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin‐Sensitive Magnetic Resonance Imaging and 18F‐Fluorodopa‐Positron Emission Tomography

open access: yesMovement Disorders, Volume 40, Issue 4, Page 716-726, April 2025.
Abstract Background Central synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), involve alpha‐synuclein accumulation and dopaminergic cell loss in the substantia nigra (SN) and locus coeruleus (LC).
Paula Trujillo   +10 more
wiley   +1 more source

Glaucoma animal models in rabbits: State of the art and perspectives—A review

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 3, Page 429-440, March 2025.
Glaucoma, a visual thief, is characterized by elevated intraocular pressure (IOP) and loss of retinal ganglion cells (RGCs). Selecting suitable animals for preclinical models is of great significance in research on the prevention, early screening, and effective treatments of glaucoma.
Rong Hu   +4 more
wiley   +1 more source

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

open access: yesFrontiers in Cell and Developmental Biology
The mechanism underlying the differentiation of the dorsal midbrain into two morphologically and functionally distinct compartments, the inferior colliculus (IC) and superior colliculus (SC), which process auditory and visual information, respectively ...
Hong-Nhung Tran   +2 more
doaj   +1 more source

An investigation regarding cellular, synaptic and glial processing in the inferior colliculi

open access: yes
The inferior colliculus (IC) is an integral centre of auditory processing. Neuronal processing of sound within IC is well established, as are its afferent and efferent projections. The IC is a complex structure that can be divided into sub-regions that undertake different aspects of processing.
openaire   +2 more sources

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