Results 41 to 50 of about 5,983 (191)

Removal of GABAA receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations [PDF]

, 2011
We investigated the behavioral significance of fast synaptic inhibition by αβγ2-type GABA(A) receptors on parvalbumin (Pv) cells. The GABA(A) receptor γ2 subunit gene was selectively inactivated in Pv-positive neurons by Cre/loxP recombination.
Leppa, E., Linden, A., Vekovischeva, O., Swinny, Jerome, Rantanen, V., Toppila, E., Hoger, H., Sieghart, W., Wulff, P., Wisden, W., Korpi, E.   +10 more
core   +1 more source

Decreasing predictability of visual motion enhances feed-forward processing in visual cortex when stimuli are behaviorally relevant [PDF]

, 2016
Recent views of information processing in the (human) brain emphasize the hierarchical structure of the central nervous system, which is assumed to form the basis of a functional hierarchy.
Frank Schneider, Ruben Scholle, Thilo Kellermann, Ute Habel   +3 more
core   +1 more source

Quantitative and Morphometric Measures in the Human Hippocampal Tail Using Ex Vivo Imaging Validated With Histology

Hippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT The human hippocampal tail is the posterior‐most portion of the hippocampus and has been implicated in brain disorders, such as depression, panic disorder, and epilepsy. The tail's clinical relevance and volumetric variability exhibit a need for improved characterization with high‐resolution imaging and histology at baseline.
Anne M. Alexander, Emma W. Rosenblum, Nathaniel Mercaldo, Erin‐Marie C. Smith, Chiara Mauri, Bruce Fischl, Ruopeng Wang, Matthew P. Frosch, André J. W. van der Kouwe, Jean C. Augustinack   +9 more
wiley   +1 more source

Metronidazole-Induced Encephalopathy in a Patient with End-Stage Liver Disease

Case Reports in Hepatology, 2012
Purpose. Metronidazole-induced encephalopathy (MIE) has been rarely reported. We report a case in a patient with end-stage liver disease (ESLD). Summary.
John P. Knorr, Imran Javed, Neha Sahni, Ceylan Z. Cankurtaran, Jorge A. Ortiz   +4 more
doaj   +1 more source

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

Frontiers in Molecular Neuroscience
Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy research.
Sandra M. Díaz-Rodríguez, Sandra M. Díaz-Rodríguez, Sandra M. Díaz-Rodríguez, M. Javier Herrero-Turrión, M. Javier Herrero-Turrión, M. Javier Herrero-Turrión, Carlos García-Peral, Carlos García-Peral, Ricardo Gómez-Nieto, Ricardo Gómez-Nieto, Ricardo Gómez-Nieto   +10 more
doaj   +1 more source

Plasticity in Limbic Regions at Early Time Points in Experimental Models of Tinnitus

Frontiers in Systems Neuroscience, 2020
Tinnitus is one of the most prevalent auditory disorders worldwide, manifesting in both chronic and acute forms. The pathology of tinnitus has been mechanistically linked to induction of harmful neural plasticity stemming from traumatic noise exposure ...
Michelle R. Kapolowicz, Michelle R. Kapolowicz, Lucien T. Thompson   +2 more
doaj   +1 more source

Neuromeric Organization of the Microbat Brain: Conserved and Distinct Regional Features

Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.
The fundamental neuromeric modular plan is remarkably conserved across bats and rodents. However, there are significant regional differences in the size and organization of specific derivatives (A). In addition, both Tadarida brasiliensis and Myotis myotis share similar general patterns of TH‐positive processes and tracts in the basal plate of the ...
F. Lucero‐Arteaga, A. Abrego‐Alvarez, M. Clauzure, S. Labegorra, V. Heck, A. I. Portu, M. A. Boeris, M. A. Mondino, B. Ribeiro Do‐Couto, K. Y. Tseng, M. Á. García‐Cabezas, J. L. Ferran   +11 more
wiley   +1 more source

Brainstem atrophy in focal epilepsy destabilizes brainstem-brain interactions: Preliminary findings. [PDF]

, 2019
BACKGROUND: MR Imaging has shown atrophy in brainstem regions that were linked to autonomic dysfunction in epilepsy patients. The brainstem projects to and modulates the activation state of several wide-spread cortical/subcortical regions.
Bateman, Lisa M., Goldman, Alica M., Laxer, Kenneth D., Mueller, Susanne G., Nei, Maromi   +4 more
core   +1 more source

An in vivo evaluation of Brilliant Blue G in animals and humans [PDF]

, 2008
Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans.Methods: BBG was injected into the 11 rat eyes to evaluate ...
Fiedorowicz, M., Grüterich, Martin, Haritoglou, Christos, Kampik, Anselm, May, C. A., Nentwich, Martin M., Priglinger, Siegfried G., Remy, M., Schuettauf, F., Schumann, Ricarda G., Thaler, S.   +10 more
core   +1 more source

Locus coeruleus‐entorhinal cortex tract integrity is linked to plasma tau and glial fibrillary acidic protein

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Pretangle tau inclusions from the locus coeruleus (LC) are hypothesized to propagate to the entorhinal cortex (EC) via neuron‐to‐neuron transmission along its projections. The lower integrity of the LC‐EC pathway accompanying Alzheimer's disease (AD) pathology is supported by post mortem studies, but in vivo evidence remains ...
Yuliya Patsyuk, Maxime Van Egroo, Elise Beckers, Elouise A. Koops, Nicholas J. Ashton, Shorena Janelidze, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Benedikt A. Poser, Heidi I. L. Jacobs   +10 more
wiley   +1 more source