Results 61 to 70 of about 6,064 (229)

Brain and retina in Alzheimer's disease: Pathological intersections and estimates from imaging

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract Recent studies have highlighted retinal optical coherence tomography (OCT) imaging as a promising biomarker for the early detection of Alzheimer's disease (AD). This review connects AD brain pathology – particularly amyloid beta (Aβ), tau, and vascular changes – with corresponding retinal changes.
M. Amin Banihashemi   +9 more
wiley   +1 more source

Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]

open access: yes, 2011
Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico   +6 more
core   +2 more sources

Automated Segmentation of the Pituitary and Pineal Glands

open access: yesHuman Brain Mapping, Volume 46, Issue 15, October 15, 2025.
This work presents a deep‐learning‐based tool for automatic segmentation of the pituitary and pineal glands. It has two novel aspects: it considers the anterior and posterior lobes as separate labels rather than a single, combined structure, and it is also the first deep‐learning protocol for pineal gland segmentation. ABSTRACT The pituitary and pineal
Kathleen E. Larson   +6 more
wiley   +1 more source

Jacobian Maps Reveal Under-reported Brain Regions Sensitive to Extreme Binge Ethanol Intoxication in the Rat

open access: yesFrontiers in Neuroanatomy, 2018
Individuals aged 12–20 years drink 11% of all alcohol consumed in the United States with more than 90% consumed in the form of binge drinking. Early onset alcohol use is a strong predictor of future alcohol dependence.
Qingyu Zhao   +6 more
doaj   +1 more source

MRI with fibre tracking in Cogan congenital oculomotor apraxia [PDF]

open access: yes, 2018
Background: Congenital ocular motor apraxia (COMA) occasionally shares with Joubert syndrome (JS) and related disorders (JSRDs) a peculiar malformation, the ‘molar tooth sign' (MTS).
De Haller, Raoul   +4 more
core  

Intestinal inflammation induces glymphatic remodeling, priming early neurodegenerative signals in male mice

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Inflammatory bowel disease triggers extraintestinal manifestations, including in the central nervous system (CNS). However, the direct impact of peripheral inflammation on the CNS is largely unknown. METHODS Using a mouse model of colitis with pain and anxiety‐like behavior, we investigated the intricate pathogenic link between ...
Clara Ciampi   +20 more
wiley   +1 more source

Effects of cardiac gating on fMRI of the human auditory system [PDF]

open access: yes, 2008
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2008.Includes bibliographical references (leaves 20-22).Guimaraes et al.
Dykstra, Andrew R. (Andrew Richard)
core  

Connecting the Brain to Itself through an Emulation. [PDF]

open access: yes, 2017
Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition.
Serruya, Mijail D.
core   +3 more sources

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

open access: yes, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix   +3 more
core   +1 more source

Evaluating the In Vivo Specificity of [18F]UCB-H for the SV2A Protein, Compared with SV2B and SV2C in Rats Using microPET

open access: yesMolecules, 2019
The synaptic vesicle protein 2 (SV2) is involved in synaptic vesicle trafficking. The SV2A isoform is the most studied and its implication in epilepsy therapy led to the development of the first SV2A PET radiotracer [18F]UCB-H.
Maria Elisa Serrano   +11 more
doaj   +1 more source

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