Results 91 to 100 of about 456,304 (239)

Impacts of perinatal nicotine exposure on nicotinic acetylcholine receptor expression and glutamatergic synaptic transmission in the mouse auditory brainstem

The Journal of Physiology, Volume 603, Issue 9, Page 2857-2876, 1 May 2025.
Abstract figure legend Developmental nicotine exposure is known to cause a myriad of health defects including auditory processing deficits. In human and animal studies, nicotine exposure can lead to impaired auditory temporal processing and disrupted glutamate synapse development within the auditory cortex.
Mackenna Wollet, Abram Hernandez, Kaila Nip, Brett Ginsburg, Jason R. Pugh, Jun Hee Kim   +5 more
wiley   +1 more source

Electrosensory midbrain neurons optimally decode ascending input during object localization

The Journal of Physiology, Volume 603, Issue 10, Page 3123-3139, 15 May 2025.
Abstract figure legend The electrosensory system of weakly electric fish relies on a self‐generated oscillating electric field called the electric organ discharge (EOD). Stimuli, such as prey, cause amplitude modulations (AMs) of the EOD. In this study, we used spatially localized AMs that mimic prey stimuli at different locations on the fish's skin ...
Myriah Haggard, Maurice J. Chacron
wiley   +1 more source

Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 768-779, April 2025.
ABSTRACT Objective Visual disability in Parkinson's disease (PD) is not fully explained by retinal neurodegeneration. We aimed to delineate the brain substrate of visual dysfunction in PD and its association with retinal thickness. Methods Forty‐two PD patients and 29 controls underwent 3‐Tesla MRI, retinal spectral‐domain optical coherence tomography,
Asier Erramuzpe, Ane Murueta‐Goyena, Antonio Jimenez‐Marin, Marian Acera, Sara Teijeira‐Portas, Rocío Del Pino, Tamara Fernández‐Valle, Ibai Diez, Unai Sainz‐Lugarezaresti, Naroa Ibarretxe‐Bilbao, Unai Ayala, Maitane Barrenechea, Alberto Cabrera‐Zubizarreta, Jesús Cortés, Juan Carlos Gómez‐Esteban, Iñigo Gabilondo   +15 more
wiley   +1 more source

A Co-culture Model for Determining the Target Specificity of the de novo Generated Retinal Ganglion Cells

Bio-Protocol, 2017
In glaucoma, the output neurons of the retina, the retinal ganglion cells (RGCs), progressively degenerate, leading to irreversible blindness (Ahram et al., 2015).
Pooja Teotia, Matthew Van Hook, Iqbal Ahmad   +2 more
doaj   +1 more source

Frequency discrimination and stimulus deviance in the inferior colliculus and cochlear nucleus

Front. Neural Circuits, 2013
Auditory neurons that exhibit stimulus-specific adaptation (SSA) decrease their response to common tones while retaining responsiveness to rare ones. We recorded single-unit responses from the inferior colliculus (IC) where SSA is known to occur and we ...
Yaneri A Ayala, D. Pérez-González, D. Duque, Israel Nelken, M. Malmierca   +4 more
semanticscholar   +1 more source

In vivo Probabilistic Structural Atlas of the Inferior and Superior Colliculi, Medial and Lateral Geniculate Nuclei and Superior Olivary Complex in Humans Based on 7 Tesla MRI

Frontiers in Neuroscience, 2019
Despite extensive neuroimaging research of primary sensory cortices involved in auditory and visual functions, subcortical structures within these domains, such as the inferior and superior colliculi, the medial and lateral geniculate nuclei and the ...
María G. García-Gomar, Christian Strong, Nicola Toschi, Nicola Toschi, Kavita Singh, Bruce R. Rosen, Lawrence L. Wald, Marta Bianciardi   +7 more
doaj   +1 more source

Calibration and reference simulations for the auditory periphery model of Verhulst et al. 2018 version 1.2 [PDF]

arXiv, 2019
This document describes a comprehensive procedure of how the biophysical model published by Verhulst et al. (2018) can be calibrated on the basis of reference auditory brainstem responses. Additionally, the filter design used in two of the model stages, cochlear nucleus (CN) and inferior colliculus (IC), is described in detail.
arxiv  

Functional Magnetic Resonance Spectroscopy in the mouse [PDF]

arXiv, 2020
Functional magnetic resonance spectroscopy (fMRS) quantifies metabolic variations upon presentation of a stimulus and can therefore provide complementary information compared to functional magnetic resonance imaging (fMRI). However, to our knowledge, fMRS has not yet been performed in the mouse, despite that murine models are crucial for basic and ...
arxiv  

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Frontiers in Cell and Developmental Biology
The mechanism underlying the differentiation of the dorsal midbrain into two morphologically and functionally distinct compartments, the inferior colliculus (IC) and superior colliculus (SC), which process auditory and visual information, respectively ...
Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong   +2 more
doaj   +1 more source

Low-threshold potassium currents stabilize IID-sensitivity in the inferior colliculus.

Frontiers in Neural Circuits, 2012
The inferior colliculus (IC) is a midbrain nucleus that exhibits sensitivity to differences in interaural time and intensity (ITDs and IIDs) and integrates information from the auditory brainstem to provide an unambiguous representation of sound location
Anita eKarcz, Anita eKarcz, Rudolf eRübsamen, Cornelia eKopp-Scheinpflug, Cornelia eKopp-Scheinpflug   +4 more
doaj   +1 more source