Quasiperiodic rhythms of the inferior olive. [PDF]
PLoS Computational Biology, 2019 Inferior olivary activity causes both short-term and long-term changes in cerebellar output underlying motor performance and motor learning. Many of its neurons engage in coherent subthreshold oscillations and are extensively coupled via gap junctions ...
Mario Negrello +8 more
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Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons. [PDF]
PLoS Computational Biology, 2020 We previously proposed, on theoretical grounds, that the cerebellum must regulate the dimensionality of its neuronal activity during motor learning and control to cope with the low firing frequency of inferior olive neurons, which form one of two major ...
Huu Hoang +7 more
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Heterogeneous Expression of T-type Ca2+ Channels Defines Different Neuronal Populations in the Inferior Olive of the Mouse [PDF]
Frontiers in Cellular Neuroscience, 2016 The neurons in the inferior olive express subthreshold oscillations in their membrane potential. This oscillatory activity is known to drive synchronous activity in the cerebellar cortex and plays a role in motor learning and motor timing.
Paolo Bazzigaluppi, Marcel T G De Jeu
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Neurons of the inferior olive respond to broad classes of sensory input while subject to homeostatic control. [PDF]
J Physiol, 2019 Cerebellar Purkinje cells integrate sensory information with motor efference copies to adapt movements to behavioural and environmental requirements. They produce complex spikes that are triggered by the activity of climbing fibres originating in neurons
Ju C +8 more
europepmc +2 more sources
Aperiodic rhythms of the inferior olive
PLOS Computational Biology, 2018 Inferior olivary activity causes both short-term and long-term changes in cerebellar output underlying motor adaptation and motor learning, respectively. Many of its neurons engage in coherent subthreshold oscillations and are extensively coupled via gap
P. Warnaar +8 more
semanticscholar +6 more sources
Frontocerebellar connectivity: climbing through the inferior olive [PDF]
Frontiers in Neuroscience, 2010 Is there a role of cerebellum beyond motor control? Neuroanatomical studies in non-human primates have shown connections between the cerebellum and non-motor cortical areas of the frontal lobe (Strick et al., 2009). These studies have not only supported the theoretical framework of how the cerebellum is involved in motor control but also forward models
Rui M Costa +4 more
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The superior colliculus projection upon the macaque inferior olive. [PDF]
Brain Struct Funct, 2023 Abstract Saccade accommodation is a productive model for exploring the role of the cerebellum in behavioral plasticity. In this model, the target is moved during the saccade, gradually inducing a change in the saccade vector as the animal adapts.
May PJ, Warren S, Kojima Y.
europepmc +4 more sources
A disynaptic basal ganglia connection to the inferior olive: potential for basal ganglia influence on cerebellar learning [PDF]
Frontiers in Systems Neuroscience, 2023 Recent studies have shown that the cerebellum and the basal ganglia are interconnected at subcortical levels. However, a subcortical basal ganglia connection to the inferior olive (IO), being the source of the olivocerebellar climbing fiber system, is ...
Tom J. H. Ruigrok +4 more
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Cerebellar and vestibular nuclear synapses in the inferior olive have distinct release kinetics and neurotransmitters [PDF]
eLife, 2020 The inferior olive (IO) is composed of electrically-coupled neurons that make climbing fiber synapses onto Purkinje cells. Neurons in different IO subnuclei are inhibited by synapses with wide ranging release kinetics.
Josef Turecek, Wade G Regehr
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Designing AAV Vectors for Monitoring the Subtle Calcium Fluctuations of Inferior Olive Network in vivo [PDF]
Frontiers in Cellular Neuroscience, 2022 Adeno-associated viral (AAV) vectors, used as vehicles for gene transfer into the brain, are a versatile and powerful tool of modern neuroscience that allow identifying specific neuronal populations, monitoring and modulating their activity.
Kevin Dorgans +4 more
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