Results 21 to 30 of about 800,258 (219)
Aluminium composites prepared by laser cladding assisted by friction stir processing
A laser cladding and friction stir processing hybrid method was employed to produce an Al matrix composite layer. The microstructure, phase composition, microhardness and conductivity of the composites were investigated.
Yanni Wei +4 more
doaj +1 more source
Targeted Accumulation of Macrophages Induced by Microbeam Irradiation in a Tissue-Dependent Manner
Radiation therapy (RT) is a vital component of multimodal cancer treatment, and its immunomodulatory effects are a major focus of current therapeutic strategies. Macrophages are some of the first cells recruited to sites of radiation-induced injury where
Verdiana Trappetti +8 more
doaj +1 more source
Study on thermodynamics and kinetics of chemical vapor deposition of silicon nitride
The thermodynamics and kinetics methods had been applied to study the effects of the deposition temperature, the reaction gas ratio and the dilution gas on Si _3 N _4 formation in the SiCl _4 -NH _3 -H _2 system.
Fuyuan Wang, Laifei Cheng, Shuhua Liang
doaj +1 more source
Microstructure and properties of ultrafine-grained W-25 wt.%Cu composites doped with CNTs
In the present work, the ultrafine-grained W-25 wt.%Cu composites doped with multi-walled carbon nanotubes (CNTs) have been prepared through combined processes of high-energy ball-milling, liquid-phase sintering and infiltration.
Qiao Zhang, Shuhua Liang, Longchao Zhuo
doaj +1 more source
The control of energy loss through building envelopes has always been a passive design solution for architecture and improvements in space quality. A significant factor is the control of infiltration through the geometry of the glass façades of buildings.
Amiraslan Darvish +3 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

