Results 31 to 40 of about 800,258 (219)

Some Aspects Of Infiltration Of High Speed Steel Based Composites With Iron Addition

open access: yesArchives of Metallurgy and Materials, 2015
Attempts have been made to describe the influence of the production process parameters and additions of iron powders on properties of copper infiltrated HSS based composites. The powder compositions used to produce skeletons for further infiltration were:
Madej M.
doaj   +1 more source

Histological effect of rifampicin drug in the kidney and liver of tissue of albino mice Mus Musclus

open access: yesTikrit Journal of Pure Science, 2021
The aim of this study is to investigate the histopathological changes induced by the anti-tuberculosis durg (rifampicin) in the tissues of the kidneys and liver of white male mice of Mus Musculus.
Muna Salah Rashid, Israa Abdoul Munem
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Microstructure and properties of W–Cu composites reinforced by in-situ synthesized WC particles in surface layer

open access: yesJournal of Materials Research and Technology
In the present work, cast iron was used as the carbon source to fabricate WC particle gradient-reinforced W–Cu composites. The results revealed that the surface layer of W–Cu composites after carbonization can be divided into a complete carbonization ...
Qiao Zhang   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Improvement on interfacial properties of CuW and CuCr bimetallic materials with high-entropy alloy interlayers via infiltration method

open access: yesScience and Engineering of Composite Materials
In order to achieve metallurgical bonding in the form of solid solution at the Cu/W interface and avoid the formation of intermetallic compounds, the novel high entropy alloys (HEAs) were designed on the basis of the mature high entropy alloy criteria ...
Yang Xiaohong   +5 more
doaj   +1 more source

Intraoperative infiltration against topical application of 5-fluorouracil in pterygium treatment

open access: yesDelta Journal of Ophthalmology, 2017
Purpose The aim of this study was to compare the efficacy and safety of intraoperative infiltration versus topical application of 5-fluorouracil (5-FU) as an adjuvant drug in pterygium treatment.
Basem M Ibrahim, Waled M Nada
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Comparison of analgesic efficacy of levobupivacaine, levobupivacaine and clonidine, and levobupivacaine and dexmedetomidine in wound infiltration technique for abdominal surgeries: A prospective randomized controlled study

open access: yesIndian Journal of Pain, 2017
Background: This study was designed to evaluate the postoperative analgesic efficacy of levobupivacaine (L) alone and its combination with clonidine (C) or dexmedetomidine (D) in wound infiltration technique for abdominal surgeries. Materials and Methods:
B Jyothi   +3 more
doaj   +1 more source

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