Results 41 to 50 of about 770,029 (237)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Nano Materials ScienceSimultaneous integration of rich oxygen vacancies (OVs) and twin crystals in a photocatalyst can not only significantly enhance the near-infrared (NIR) light response but also greatly improve the photocharge separation and transfer efficiency owing to ...
Xiaochuan Zhang +9 more
doaj +1 more source
Revista Ambiente & Água, 2020 The search for better living conditions has led the residents of the Brazilian semi-arid region to plant forage crops, leading to a gradual decrease in the native vegetation (Caatinga) of this region.
Willames Albuquerque Soares +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A novel method enabling in-situ additive manufactured TiB2/Cu composite with high performance
Journal of Materials Research and TechnologyIn-situ additive manufacturing method utilizes the high cooling rate of melt pool to produce composite parts with nano-scaled reinforcement and high relative density.
Yanfang Wang +8 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
JTSL (Jurnal Tanah dan Sumberdaya Lahan), 2019 Coffee plants belong to important commodities in Indonesia. In 2003, coffee productivity in Indonesia reached 725 kg ha-1 and decreased 0.41% in 2016 to 722 kg ha-1. Climate change is expected on the production of coffee crops.
Ika Lestiana Sari, Sugeng Prijono
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Acta Scientiarum Polonorum. Formatio Circumiectus, 2020 Aim of the study: The aim of the research was to determine the sensitivity of the impedance spectrometry (EIS) method to changes in electrical resistance of the soil medium caused by water infiltration. Material and methods: The research was carried
Tymoteusz Adam Zydroń +3 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source