Results 61 to 70 of about 770,029 (237)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Frontiers in OncologyMethodsCNKI, Wanfang, VIP, Sinomed, Pubmed, Web of Science, Embase, and other databases were searched. The retrieval time was from the establishment of the database to January 31, 2024.
Mengqian Li +6 more
doaj +1 more source
Intraocular Infiltration [PDF]
The American Journal of Tropical Medicine and Hygiene, 2020 Kamoi, Koju, Ohno-Matsui, Kyoko
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2000 Este trabalho foi conduzido na Área Experimental de Hidráulica, Irrigação e Drenagem do Departamento de Engenharia Agrícola da Universidade Federal de Viçosa, em Viçosa, MG, com o objetivo de se avaliar a influência de aplicações sucessivas de águas ...
Rubens Alves Oliveira +4 more
doaj +1 more source
Grounded Theory Review: An International Journal, 2023 This is a grounded theory of the basic social process of infiltration. Novice researchers, infants, foreigners and new recruits all face conceptually similar problems of being able to successfully infiltrate into an array of alien situations. The grounded theory emerged from data from the context of a novice researcher gaining and sustaining access for
Wendy Guthrie, Andy Lowe
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Effect of temporal averaging of meteorological data on predictions of groundwater recharge
Journal of Hydrology and Hydromechanics, 2018 Accurate estimates of infiltration and groundwater recharge are critical for many hydrologic, agricultural and environmental applications. Anticipated climate change in many regions of the world, especially in tropical areas, is expected to increase the ...
Batalha Marcia S. +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source