Results 91 to 100 of about 31,317 (308)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer [PDF]

, 2019
Aims Lymphovascular space invasion (LVSI) in endometrial cancer (EC) is an important prognostic variable impacting on a patient's individual recurrence risk and adjuvant treatment recommendations.
Bartosch, Carla, Bosse, Tjalling, Genestie, Catherine, Lax, Sigurd F, McCluggage, W Glenn, Nout, Remi, Oosting, Jan, Peters, Elke E M, Singh, Naveena, Smit, Huub C S H, Smit, Vincent T H B M, Van de Vijver, Koen   +11 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Imaging diagnosis: magnetic resonance imaging of diffuse leptomeningeal oligodendrogliomatosis in a dog with "dural tail sign" [PDF]

, 2018
A case of diffuse leptomeningeal oligodendrogliomatosis affecting the brain and spinal cord of a dog is presented. A 7.5-year old, male neutered Staffordshire bull terrier presented for evaluation of a chronic history of tetraparesis and seizures, with a
Anwer, Armao, Atlas, Beck, Bourekas, Canal, Celli, Chiechi, Goldsher, Graham, Guermazi, Holodny, Kneissl, Kovi, LeepHunderfund, Lipitz, Mathews, Morioka, Nakasu, Nägele, Paz-Fumagalli, Pronin, Provenzale, Rogers, Rothlisberger, Smirniotopoulos, Stoica, Tamura, Troxel, Wilms, Wisner, Young   +31 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Candidates for Intensive Local Treatment in cIIIA-N2 Non-Small Cell Lung Cancer: Deciphering the Heterogeneity [PDF]

, 2002
PurposeThe purpose of this study was to refine the heterogeneous clinical stage IIIA non-small cell lung cancer (NSCLC) with N2 nodes status (cIIIA-N2) by clinicopathological characteristics before treatment.Methods and MaterialsWe analyzed data of ...
Horinouchi, Hidehito, Goto, Yasushi, Kanda, Shintaro, Fujiwara, Yutaka, Nokihara, Hiroshi, Yamamoto, Noboru, Sumi, Minako, Tamura, Tomohide, Ohe, Yuichiro   +8 more
core   +3 more sources

Transitional cell carcinoma of urinary bladder with metastasis in lumbar vertebrae and spinal cord compression in an ocelot(Leopardus pardalis)

Pesquisa Veterinária Brasileira, 2015
This paper reports a case of nonpapillary and infiltrative transitional cell carcinoma (TCC) of the urinary bladder with metastasis of lumbar vertebrae and spinal cord compression in an adult female ocelot (Leopardus pardalis), from the Mato Grosso state,
Karen Y.R. Nakagaki, Pâmela A. Lima, Kiyoko U. Utiumi, Marco A.M. Pires, Rosana Zanatta, Fabiana M. Boabaid, Edson M. Colodel, Djeison L. Raymundo   +7 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Nomenclature revision for encapsulated follicular variant of papillary thyroid carcinoma:a paradigm shift to reduce overtreatment of indolent tumors [PDF]

, 2016
Although growing evidence points to highly indolent behavior of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), most patients with EFVPTC are treated as having conventional thyroid ...
Al Ghuzlan, Abir, Alves, Venancio A., Asa, Sylvia L., Baloch, Zubair W., Barletta, Justine A., Basolo, Fulvio, El-Naggar, Adel K., Ghossein, Ronald A., Giordano, Thomas J., Gooding, William E., Hodak, Steven P., Kakudo, Kennichi, Khanafshar, Elham, LiVolsi, Virginia A., Lloyd, Ricardo V., Maytal, Guy, Mete, Ozgur, Nikiforov, Yuri E., Nikiforova, Marina N., Nosé, Vania, Papotti, Mauro, Poller, David, Randolph, Gregory W., Sadow, Peter M., Seethala, Raja R., Tallini, Giovanni, Thompson, Lester D. R., Tischler, Arthur S., Tuttle, Michael, Wall, Kathryn B., Wenig, Bruce M.   +30 more
core   +2 more sources

Staging, Grading, and Emerging Prognostic Factors in Renal Cell Carcinoma

Kidney Cancer
Renal cell carcinoma (RCC) makes up most adult kidney cancers. The classic presentation is a spherical, well-circumscribed mass, but fewer subtypes present as more infiltrative neoplasms.
Nicole Zalles, Sean R. Williamson
doaj   +1 more source