Results 41 to 50 of about 944,552 (285)

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Nonlinear volterra equations with infinite delay

Monatshefte f�r Mathematik, 1977
This paper is concerned with the existence and stability of nonlinear Volterra equations which have infinite delay and are of the form: $$x (\varphi ) (t) = W (t, \tau ) \varphi (0) + \int\limits_\tau ^t {W (t, s)} F(s,x_s (\varphi )) ds, x_\tau (\varphi ) = \varphi \in C_u .$$
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stochastic Maximum Principle for Optimal Control of Infinitely Delayed Systems of Functional Type in Infinite Dimensions

Mathematics
This paper investigates the optimal control of a stochastic delayed system with infinite delay of general functional type. By introducing a non-anticipative path derivative and its infinite-window dual operator, we formulate the infinitely anticipated ...
Guanwei Cheng
doaj   +1 more source

Nonuniform Stability of Difference Equations with Infinite Delay

Advanced Nonlinear Studies, 2010
Abstract In this note we consider the notion of nonuniform exponential contraction for delay difference equations with infinite delay (one can argue that the only delay difference equations are those with infinite delay, since otherwise we can always bring them to the standard recurrence form in some higher-dimensional space).
Barreira, Luis, Valls, Claudia
openaire   +1 more source

Stability of Distributed Delay System with Infinite Support [PDF]

2018 IEEE Conference on Decision and Control (CDC), 2018
This paper is devoted to the stability analysis of infinite distributed delay systems. The basic idea is to model the original time-delay system into an interconnected feedback system in order to use robust analysis and especially quadratic separation. This approach has been widely used to study classical pointwise time-delay system.
Yassine Ariba, Frédéric Gouaisbaut, Alexandre Seuret, Kun Liu 0002   +3 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Qualitative analysis of Volterra-type integral equations with an infinite delay model in spaces of locally bounded κ-variation functions

Arab Journal of Basic and Applied Sciences
Integral equations with memory effects and infinite delay arise naturally in applications such as ecology, neuroscience, and viscoelasticity, among others.
Luz Marchan, Liliana Pérez, José Zambrano   +2 more
doaj   +1 more source

Infinite–Dimensional Bifurcations in Spatially Distributed Delay Logistic Equation

Mathematics, 2022
This paper investigates the questions about the local dynamics in the neighborhood of the equilibrium state for the spatially distributed delay logistic equation with diffusion. The critical cases in the stability problem are singled out.
Sergey Kashchenko
doaj   +1 more source