Results 61 to 70 of about 944,552 (285)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Solvability of Nonautonomous Fractional Integrodifferential Equations with Infinite Delay

open access: yesAdvances in Difference Equations, 2011
We study the existence and uniqueness of mild solution of a class of nonlinear nonautonomous fractional integrodifferential equations with infinite delay in a Banach space .
Li Fang
doaj   +2 more sources

Infinite Horizon Optimal Control of Stochastic Delay Evolution Equations in Hilbert Spaces

open access: yesAbstract and Applied Analysis, 2013
The aim of the present paper is to study an infinite horizon optimal control problem in which the controlled state dynamics is governed by a stochastic delay evolution equation in Hilbert spaces.
Xueping Zhu, Jianjun Zhou
doaj   +1 more source

Note on a theorem of J. Folkman on transversals of infinite families with finitely many infinite members [PDF]

open access: yes, 1981
In this note we show by a simple direct proof that Folkman's necessary and sufficient condition for an infinite family of sets with finitely many infinite members to have a transversal implies Woodall's condition.
Bry, François
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Special wave finite and infinite elements for the solution of the Helmholtz equation [PDF]

open access: yes, 2003
The theory and the formulation of the special wave finite elements are discussed, and the special integration schemes for the elements are developed.
Sugimoto, Rie
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The permanence and periodic solution of a competitive system with infinite delay, feedback control, and Allee effect

open access: yesAdvances in Difference Equations, 2018
This paper is devoted to study the permanence and periodic solution of a competitive system with infinite delay, feedback control, and the Allee effect.
Lei Shi   +4 more
doaj   +1 more source

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