Results 111 to 120 of about 382,145 (280)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

An introduction of F-graphs, a graph-theoretic representation of natural numbers

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1992
A special type of family graphs (F-graphs, for brevity) are introduced. These are cactus-type graphs which form infinite families under an attachment operation. Some of the characterizing properties of F-graphs are discussed.
E. J. Farrell
doaj   +1 more source

Families of Integral Cographs within a Triangular Array

open access: yesSpecial Matrices, 2020
The determinant Hosoya triangle, is a triangular array where the entries are the determinants of two-by-two Fibonacci matrices. The determinant Hosoya triangle mod 2 gives rise to three infinite families of graphs, that are formed by complete product ...
Ching Hsin-Yun   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A Laplacian eigenbasis for threshold graphs

open access: yesSpecial Matrices
Let GG be a graph on nn vertices. In this article, we prove that an eigenbasis of the Laplacian matrix of a star graph of order nn is also an eigenbasis of GG if and only if GG is a threshold graph. As an application of this spectral characterization, we
Macharete Rafael R.   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

On Independent Domination in Planar Cubic Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2019
A set S of vertices in a graph G is an independent dominating set of G if S is an independent set and every vertex not in S is adjacent to a vertex in S.
Abrishami Gholamreza   +2 more
doaj   +1 more source

Distance-Transitivity in Infinite Graphs

open access: yesJournal of Combinatorial Theory, Series B, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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