Results 91 to 100 of about 25,369 (266)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Families of Integral Cographs within a Triangular Array
Special Matrices, 2020 The determinant Hosoya triangle, is a triangular array where the entries are the determinants of two-by-two Fibonacci matrices. The determinant Hosoya triangle mod 2 gives rise to three infinite families of graphs, that are formed by complete product ...
Ching Hsin-Yun +2 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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A Laplacian eigenbasis for threshold graphs
Special MatricesLet GG be a graph on nn vertices. In this article, we prove that an eigenbasis of the Laplacian matrix of a star graph of order nn is also an eigenbasis of GG if and only if GG is a threshold graph. As an application of this spectral characterization, we
Macharete Rafael R. +3 more
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
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On Independent Domination in Planar Cubic Graphs
Discussiones Mathematicae Graph Theory, 2019 A set S of vertices in a graph G is an independent dominating set of G if S is an independent set and every vertex not in S is adjacent to a vertex in S.
Abrishami Gholamreza +2 more
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Distance-Transitivity in Infinite Graphs
Journal of Combinatorial Theory, Series B, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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Retracts of Infinite Hamming Graphs
Journal of Combinatorial Theory, Series B, 1997 A Hamming graph is a Cartesian product of complete graphs. We show that (finite or infinite) quasi-median graphs, which are a generalization of median graphs, are exactly the retracts of Hamming graphs. This generalizes a result of \textit{H. J. Bandelt} [J.
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
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