Results 81 to 90 of about 25,369 (266)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The incidence chromatic number of some graph
International Journal of Mathematics and Mathematical Sciences, 2005 The concept of the incidence chromatic number of a graph was introduced by Brualdi and Massey (1993). They conjectured that every graph G can be incidence colored with Δ(G)+2 colors.
Liu Xikui, Li Yan
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
3-Chloro-4-hydroxyfuran-2(5H)-one
Acta Crystallographica Section E, 2009 In the title compound, C4H3ClO3, molecules are linked via O—H...O hydrogen bonds into an infinite chain with graph-set motif C(6) along the c axis.
Na Zhang +4 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Mathematics OpenThe cycle graph of a graph G is the graph [Formula: see text] whose vertices are the induced cycles of G and where two vertices are adjacent if and only if they are distinct induced cycles that share a common edge.
Severino V. Gervacio, Yvette F. Lim
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
An introduction of F-graphs, a graph-theoretic representation of natural numbers
International Journal of Mathematics and Mathematical Sciences, 1992 A special type of family graphs (F-graphs, for brevity) are introduced. These are cactus-type graphs which form infinite families under an attachment operation. Some of the characterizing properties of F-graphs are discussed.
E. J. Farrell
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