Results 101 to 110 of about 216,697 (310)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret   +4 more
wiley   +1 more source

Existence of infinitely many solutions for semilinear elliptic equations

open access: yesElectronic Journal of Differential Equations, 2016
In this article, we study the existence and infinitely many solutions for the elliptic boundary-value problem $$\displaylines{ -\Delta u+a(x)u=f(x,u) \quad\text{in }\Omega, \cr u=0 \quad\text{on }\partial\Omega.
Hui-Lan Pan, Chun-Lei Tang
doaj  

Infinitely many solutions to quasilinear Schrödinger equations with critical exponent

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
This paper is concerned with the following quasilinear Schrödinger equations with critical exponent: \begin{equation*}\label{eqS0.1} - \Delta _p u+ V(x)|u|^{p-2}u - \Delta _p(|u|^{2\omega}) |u|^{2\omega-2}u = a k(x)|u|^{q-2}u+b |u|^{2\omega p^{*}-2}
Li Wang, Jixiu Wang, Xiongzheng Li
doaj   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

INFINITELY MANY SOLUTIONS FOR A CLASS OF SUBLINEAR SCHRÖDINGER EQUATIONS

open access: yesTaiwanese Journal of Mathematics, 2015
In this paper, we deal with the existence of infinitely many solutions for a class of sublinear Schrodinger equation $$ \left\{ \begin{array}{ll} -\triangle u+V(x)u=f(x, u), \ \ \ \ x\in {\mathbb{R}}^{N},\\ u\in H^{1}({\mathbb{R}}^{N}). \end{array} \right. $$ Under the assumptions that $\inf_{{\mathbb{R}}^{N}}V(x) >0$ and $f(x,
Chen, Jing, Tang, X. H.
openaire   +3 more sources

Using High‐Throughput Screening to Identify Crosslinking Peptides That Control Cell‐Mediated Matrix Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu   +3 more
wiley   +1 more source

Infinitely many solutions for Hamiltonian system with critical growth

open access: yesAdvances in Nonlinear Analysis
In this article, we consider the following elliptic system of Hamiltonian-type on a bounded domain:−Δu=K1(∣y∣)∣v∣p−1v,inB1(0),−Δv=K2(∣y∣)∣u∣q−1u,inB1(0),u=v=0on∂B1(0),\left\{\begin{array}{ll}-\Delta u={K}_{1}\left(| y| ){| v| }^{p-1}v,\hspace{1.0em ...
Guo Yuxia, Hu Yichen
doaj   +1 more source

Infinitely Many Sign-Changing Solutions for Some Nonlinear Fourth-Order Beam Equations

open access: yesAbstract and Applied Analysis, 2013
Several new existence theorems on positive, negative, and sign-changing solutions for the following fourth-order beam equation are obtained: u(4)=f(t,u(t)),   t∈[0,1];  u(0)=u(1)=u′′(0)=u′′(1)=0, where f∈C([0,1]×ℝ1,ℝ1).
Ying Wu, Guodong Han
doaj   +1 more source

Robust pH Sensing Using a Graphene Oxide and Covalent Organic Frameworks Composite for Gastro‐esophageal Reflux Disease Diagnosis

open access: yesAdvanced Healthcare Materials, EarlyView.
A stable composite pH sensor is developed by coating graphene oxide (GO) nanosheets with covalent organic frameworks (COFs) to improve stability and sensitivity in acidic environments. The GO/COFs sensor demonstrates high selectivity, linearity, and biocompatibility, offering a promising strategy for continuous pH monitoring in gastro‐esophageal reflux
Ahmed H. M. Salem   +6 more
wiley   +1 more source

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