Results 1 to 10 of about 87,594 (119)

Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

iScience, 2022
Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty, Luca Bettamin, Anne Thouard, Karine Bourgade, Sophie Allart, Guilhem Larrieu, Cécile Evelyne Malnou, Daniel Gonzalez-Dunia, Elsa Suberbielle   +8 more
doaj   +1 more source

Identification of SARS-CoV-2 variants using viral sequencing for the Centers for Disease Control and Prevention genomic surveillance program

BMC Infectious Diseases, 2022
Background The Centers for Disease Control and Prevention contracted with laboratories to sequence the SARS-CoV-2 genome from positive samples across the United States to enable public health officials to investigate the impact of variants on disease ...
Chirayu Goswami, Michael Sheldon, Christian Bixby, Mehdi Keddache, Alexander Bogdanowicz, Yihe Wang, Jonathan Schultz, Jessica McDevitt, James LaPorta, Elaine Kwon, Steven Buyske, Dana Garbolino, Glenys Biloholowski, Alex Pastuszak, Mary Storella, Amit Bhalla, Florence Charlier-Rodriguez, Russ Hager, Robin Grimwood, Shareef A. Nahas   +19 more
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The main steps of TCR signalingNegative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses

Biomedical Journal, 2022
The activity of T cells is finely controlled by a set of negative regulators of T-cell antigen receptor (TCR)-mediated signaling. However, how those negative regulators are themselves controlled to prevent ineffective TCR-mediated responses remain poorly
Suzanne Mélique, Cui Yang, Renaud Lesourne   +2 more
doaj   +1 more source

Innate Immune Response to Viral Infections at the Maternal-Fetal Interface in Human Pregnancy

Frontiers in Medicine, 2021
The placenta, the first and largest organ to develop after conception, not only nurtures and promotes the development of the conceptus, but, it also functions as a barrier against invading pathogens.
Ana Espino, Hicham El Costa, Julie Tabiasco, Reem Al-Daccak, Nabila Jabrane-Ferrat   +4 more
doaj   +1 more source

Hepatitis E Virus Infection: Neurological Manifestations and Pathophysiology

Pathogens, 2021
Hepatitis E virus (HEV) is the first cause of viral hepatitis in the world. While the water-borne HEV genotypes 1 and 2 are found in developing countries, HEV genotypes 3 and 4 are endemic in developed countries due to the existence of animal reservoirs,
Sébastien Lhomme, Florence Abravanel, Pascal Cintas, Jacques Izopet   +3 more
doaj   +1 more source

Connecting the Tangent Function to Cardinality: A Method for Introducing Set Theory to High School Students

Journal of Mathematics Education at Teachers College, 2019
High school students often ask questions about the nature of infinity. When contemplating what the “largest number” is, or discussing the speed of light, students bring their own ideas about infinity and asymptotes into the conversation.
Steve Deihl, Mara P. Markinson
doaj   +3 more sources

A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage

eLife, 2022
The ability to proliferate is a common feature of most T-cell populations. However, proliferation follows different cell-cycle dynamics and is coupled to different functional outcomes according to T-cell subsets.
Jérémy Argenty, Nelly Rouquié, Cyrielle Bories, Suzanne Mélique, Valérie Duplan-Eche, Abdelhadi Saoudi, Nicolas Fazilleau, Renaud Lesourne   +7 more
doaj   +1 more source

End-to-End Deep Graph Convolutional Neural Network Approach for Intentional Islanding in Power Systems Considering Load-Generation Balance

Sensors, 2021
Intentional islanding is a corrective procedure that aims to protect the stability of the power system during an emergency, by dividing the grid into several partitions and isolating the elements that would cause cascading failures. This paper proposes a
Zhonglin Sun, Yannis Spyridis, Thomas Lagkas, Achilleas Sesis, Georgios Efstathopoulos, Panagiotis Sarigiannidis   +5 more
doaj   +1 more source

The Contribution of Human Herpes Viruses to γδ T Cell Mobilisation in Co-Infections

Viruses, 2021
γδ T cells are activated in viral, bacterial and parasitic infections. Among viruses that promote γδ T cell mobilisation in humans, herpes viruses (HHVs) occupy a particular place since they infect the majority of the human population and persist ...
Fanny Martini, Eric Champagne
doaj   +1 more source

The Discovery of Black Light [PDF]

Философия и космология, 2021
This article is the beginning of a reexpresson, and partial revision, of my book Black Light. The questions that I discuss in this article are listed in the below list of sections. In Sections 7, 8, 27, and 28, I discuss my discovery of black light. The
Dan Howitt
doaj   +1 more source