Results 41 to 50 of about 199,378 (307)

Be(com)ing a Christian Is Not a Social Identity: Kierkegaard and the Refusal of Social Roles

Religions, 2021
This paper examines aspects of Kierkegaard’s authorship in relation to contemporary identity politics. Specifically, it argues that several pseudonymous voices in Kierkegaard’s works and identity politics share the contention that ethics presupposes ...
Charles Djordjevic
doaj   +1 more source

NATURE DENATURED IN FLANN O’BRIEN’S THE THIRD POLICEMAN [PDF]

University of Bucharest Review. Literary and Cultural Studies Series, 2012
The Third Policeman, the last and most complex of the major novels of „Flann O‟Brien‟ – the Irish satirical writer Brian O‟Nolan – is a latecomer in a European movement of antinaturalism begun by Rimbaud, Zola and Huysmans in the last quarter of the ...
Richard Witt
doaj  

Asymptotic U(1) charges at spatial infinity [PDF]

, 2017
A bstractLarge gauge symmetries in Minkowski spacetime are often studied in two distinct regimes: either at asymptotic (past or future) times or at spatial infinity. By working in harmonic gauge, we provide a unified description of large gauge symmetries
Miguel Campiglia, R. Eyheralde
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III model

Frontiers in Molecular Biosciences
Sanfilippo syndrome (MPSIII) is a neurodegenerative disorder caused by enzyme deficiencies, leading to the toxic accumulation of heparan sulfate oligosaccharides in the brain.
Mathilde Larribau, Myriam Rouahi, Christophe Santiago, Jérôme Ausseil, Jérôme Ausseil, Zoubida Karim   +5 more
doaj   +1 more source

Mehmed Emīn Üsküdarī’s Sharh al-Barahīn al-khamsa on Infinity [PDF]

Nazariyat: Journal for the History of Islamic Philosophy and Sciences, 2022
This article examines the form and content of Sharh al-Barāhīn al-khamsa, written by Mehmed Emīn Üsküdārī (d. 1149/1736-37), an important figure of eighteenth-century Ottoman Turkish philosophical thought, on the problems of the finitude of extensions ...
M. Necmeddin Beşikci
doaj  

Assessing risk of damage to posterior ankle structures during total ankle arthroplasty

Bone & Joint Open, 2021
Aims: Arthroplasty has become increasingly popular to treat end-stage ankle arthritis. Iatrogenic posterior neurovascular and tendinous injury have been described from saw cuts. However, it is hypothesized that posterior ankle structures could be damaged
Christopher J. Callaghan, John C. McKinley   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Fine-tuning levels of filamins a and b as a specific mechanism sustaining Th2 lymphocyte functions

Nature Communications
Augmenting the portfolio of therapeutics for type 2-driven diseases is crucial to address unmet clinical needs and to design personalized treatment schemes. An attractive therapy for such diseases would consist in targeting the recruitment of T helper 2 (
Kilian Maire, Léa Chamy, Samira Ghazali, Manon Carratala-Lasserre, Margot Zahm, Clément Bouisset, Arnaud Métais, Lucie Combes-Soia, Lidia de la Fuente-Vizuete, Hussein Trad, Adeline Chaubet, Magali Savignac, Anne Gonzalez de Peredo, Arun Subramaniam, Olivier Joffre, Pierre G. Lutz, Isabelle Lamsoul   +16 more
doaj   +1 more source

Embodiment of infinity in mathematics

Frontiers in Psychology
In this article, we discuss the embodiment of infinity as one of fundamental concepts in mathematics. In contrast to the embodiment of many other mathematical concepts, the embodiment of infinity is an endless dynamic process.
Omid Khatin-Zadeh, Danyal Farsani, Zahra Eskandari   +2 more
doaj   +1 more source